Present paper studies the rarefied flow of binary Neon–Argon mixture in plane channel induced by pressure gradient and counteracting drag by moving walls. The problem is studied numerically using Direct Simulation Monte Carlo method. It is demonstrated that drag force induced by motion of channel walls leads to the effect of enhanced mixture separation. Stronger separation effects are unexpectedly observed for denser gases and thorough explanation for such behavior is provided. It was also shown that gas flow rate in the channel decreases non-monotonically with increasing speed of the walls, having local minimum at wall speeds close to mean thermal speed of molecules. The influence of other parameters, such as channel length and accommodation coefficient on the walls, was also examined.