Upper Punctal Occlusion versus Lower Punctal Occlusion in Dry Eye

Feng, Chen; Wang, Jianhua; Chen, Wei; Shen, Meixiao; Xu, Suzhong; Liu, Fan

doi:10.1167/iovs.09-5097

Cited by 31 publications

(28 citation statements)

References 25 publications

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“…They can, thus, improve tear volume and have similar efficacy with upper or lower tear duct occlusion [77]. In severe dry eyes, oral cholinergic agonists such as pilocarpine and cevimeline may improve symptoms by stimulating lacrimal gland secretion [78, 79].…”

Section: Treatment From the Aging Perspectivementioning

confidence: 99%

Aging: A Predisposition to Dry Eyes

Sharma

Hindman

2014

Journal of Ophthalmology

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Dry eye syndrome is a disease of the ocular surface and tear film that is prevalent in older adults. Even though the degree of visual acuity loss in dry eye patients is commonly mild-to-moderate, in the aging population, this minimal change in visual status can lead to a significant decrease in visual function and quality of life. A healthy ocular surface is maintained by appropriate tear production and tear drainage, and deficiencies in this delicate balance can lead to dryness. In the aging eye, risk factors such as polypharmacy, androgen deficiency, decreased blink rates, and oxidative stress can predispose the patient to developing dry eye that is frequently more severe, has higher economic costs, and leads to worse consequences to the well-being of the patient. Understanding why elderly patients are at higher risk for developing dry eyes can provide insights into the diagnosis and management of the growing number of older adults struggling with dry eye and minimize the burden of disease on our aging population.

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Section: Treatment From the Aging Perspectivementioning

confidence: 99%

Aging: A Predisposition to Dry Eyes

Sharma

Hindman

2014

Journal of Ophthalmology

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“…This OCT system was previously described. 26,[28][29][30][31][32][33][34][35] Briefly, the superluminescent diode-based light source (Superlum, Broadlighter, D840-HP; Superlumdiodes, Ltd., Moscow, Russia) provided a beam of 840-nm wavelength and 50-nm bandwidth with a 7.2-mm scan depth in air. The longitudinal resolution of this SD-OCT system was approximately 6 lm in tissue, the lateral resolution was approximately 15 lm, and the scan speed was 24 frames per second.…”

Section: Anterior Segment Octmentioning

confidence: 99%

“…The detailed procedure of the image-processing software has been described, and the repeatability of these measurements was verified in our previous studies. [28][29][30][31][32]35 Statistical Analysis…”

Section: Anterior Segment Octmentioning

confidence: 99%

“…25,26 With high-resolution scans and high acquisition speeds, SD-OCT provides high sensitivity and specificity in diagnosis of dry eye. 27 In the study reported here, we used a custom-built anterior-segment SD-OCT instrument that was described in previous studies 26,[28][29][30][31][32][33][34][35] to measure pre-and postoperative tear menisci in patients undergoing LASIK surgeries using either a microkeratome or a femtosecond laser to create the corneal flap.…”

mentioning

confidence: 99%

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Tear Menisci After Laser In Situ Keratomileusis With Mechanical Microkeratome and Femtosecond Laser

Xie

Zhang

Chen

et al. 2014

Invest. Ophthalmol. Vis. Sci.

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L. Tear menisci after laser in situ keratomileusis with mechanical microkeratome and femtosecond laser. Invest Ophthalmol Vis Sci. 2014;55:5806-5812. DOI:10.1167/ iovs.13-13669 PURPOSE. To investigate the effect on tear menisci after laser in situ keratomileusis (LASIK) with flap creation by either microkeratome or femtosecond laser.METHODS. Sixty eyes of 30 myopes were analyzed. Fifteen patients underwent LASIK with Moria II microkeratome, and the other 15 patients with 60-KHz IntraLase femtosecond laser. Upper and lower tear meniscus parameters of height (UTMH, LTMH) and area (UTMA, LTMA) were measured by SD-OCT preoperatively and 1 week, 1 month, and 3 months postoperatively.RESULTS. Compared with the baseline values, all tear meniscus parameters decreased significantly at each postoperative time point (all P < 0.01) in both groups. LTMH increased significantly between 1 week and 1 month and between 1 and 3 months after surgery in the microkeratome (both P < 0.01) and femtosecond laser groups (P < 0.01, P ¼ 0.012, respectively). There were significant increases in LTMA between 1 week and 1 month after surgery in the microkeratome group (P < 0.01) and in the femtosecond laser group (P ¼ 0.028). There were no significant differences in UTMH, UTMA, LTMH, or LTMA between two groups. The depth of ablation was negatively correlated with the LTMA at 1 week after surgery (R ¼ À0.256, P ¼ 0.049) for all patients.CONCLUSIONS. There were no significant differences in the tear meniscus parameters between the microkeratome and femtosecond laser groups. The depth of ablation was significantly correlated with the LTMA only at 1 week after surgery.

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“…Some patients with dry eyes were identified in this study. These patients generally will have recurrence within 1 -2 years of the first dry-eye symptoms [9][10][11]. During the initial stages, their symptoms were off and on but when the course of the disease become protracted, the lacrimal punctum may be blocked.…”

Section: Discussionmentioning

confidence: 99%