Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells

Comparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast cancer cells: targeting p53 for anticancer therapy

“…17 However, the toxicity of AgNPs depends on their size, concentration, and surface functionalization. 18 Park et al demonstrated that the size of AgNPs is an important factor for cytotoxicity, inflammation, and genotoxicity. 19 The evaluation of toxicity of AgNPs has been carried out in different cellular models, including human lung fibroblasts, 20 BRL3A rat liver cells, 21 PC-12 neuroendocrine cells, 22 human alveolar epithelial cells, 23 germline stem cells, 24 breast cancer cells, 10 and human lung cancer cells.…”

Effects triggered by platinum nanoparticles on primary keratinocytes

“…Such a mechanism has already been described for silver NPs. 25,26 Cells treated with NPs displayed changed morphology after 24 and 48 hours of incubation in comparison to control cells, but only when analyzed by TEM. No morphological changes could be observed for 5.8 nm PtNPs treated for 24 hours, when bright-field microscopy was applied.…”

Analysis of engineered nanomaterials in complex matrices (environment and biota): General considerations and conceptual case studies

“…Focused ion beam SEM is used to reveal subsurface layers revealed by atomic milling and then acquire images at each newly exposed plane. This method has been used recently to show nano-Ag particles inside cells, in conjunction with EDS for chemical confirmation [43]. The approach strikes a good balance between providing nano-scale resolution, avoiding embedding, using cryogenic techniques to preserve specimens, and enabling internal imaging plus threedimensional (3D) reconstruction.…”

“…1, pp. [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49]2012 # 2011 SETAC Printed in the USA DOI: 10.1002/etc.723 This paper evolved from discussions held at a SETAC-endorsed Technical Workshop held at Clemson University in August, 2010. The workshop was sponsored by the United States Environmental Protection Agency (U.S. EPA), Arcadis-US, and the Clemson University Institute of Environmental Toxicology.…”