Urban contributions of glyphosate and its degradate AMPA to streams in the United States

Kolpin, Dana W.; Thurman, E. Michael; Lee, Edward A.; Meyer, Michael T.; Furlong, Edward T.; Glassmeyer, Susan T.

doi:10.1016/j.scitotenv.2005.01.028

Cited by 224 publications

(144 citation statements)

References 33 publications

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“…Italy (Lombardy Region) up to 96 Sampling intensity increased due to more concern about glyphosate residues during than previously, 2008Di Guardo and Finizio, 2018 analysis methods of better sensitivity and accuracy (Huhn, 2018). Glyphosate and AMPA were found to emerge in surface water by leaching from agricultural areas in the US and Canada (Edwards et al, 1980;Feng et al, 1990;Payne et al, 1990;Payne, 1992;Battaglin et al, 2005Battaglin et al, , 2009Kolpin et al, 2006;Struger et al, 2008;Shipitalo and Owens, 2011;Coupe et al, 2012;Glozier et al, 2012) among others by the US Geological Survey (Kolpin et al, 2006), at concentrations up to 5,200 and 400 ng/l, respectively in the US North Appalache and the Midwest (Battaglin et al, 2005(Battaglin et al, , 2009 in regions, where the use of glyphosate-based pesticide formulations is substantial e.g., due to the cultivation of GT (RR) crops (Cuhra, 2015). Glyphosate has also been indicated as a significant water pollutant from intensive agriculture in Mexico (Ruiz-Toledo et al, 2014).…”

Section: Exposure To Glyphosate-environmental and Food Analysis Humamentioning

confidence: 99%

“…glyphosate have also been indicated (Kolpin et al, 2006;Botta et al, 2009;Hanke et al, 2010;Glozier et al, 2012) to contribute to environmental contamination. Soil contamination appears to show a closer correlation with agricultural usage intensity, while water contamination results from run-off events by precipitation (Landry et al, 2005;Maqueda et al, 2017;Poiger et al, 2017).…”

Section: Exposure To Glyphosate-environmental and Food Analysis Humamentioning

confidence: 99%

See 1 more Smart Citation

Re-registration Challenges of Glyphosate in the European Union

Székacs

Darvas

2018

Front. Environ. Sci.

106

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Section: Exposure To Glyphosate-environmental and Food Analysis Humamentioning

confidence: 99%

Section: Exposure To Glyphosate-environmental and Food Analysis Humamentioning

confidence: 99%

Re-registration Challenges of Glyphosate in the European Union

Székacs

Darvas

2018

Front. Environ. Sci.

106

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“…Since 1997, its agricultural use has increased considerably as a result of the introduction of genetically-engineered "Roundup Ready" glyphosate tolerant varieties of soybean, cotton and maize (Giesy et al, 2000;Woodburn, 2000). It has become one of the most commonly-used herbicides for agricultural weed control worldwide (Giesy et al, 2000;Kolpin et al, 2006), and also for domestic and industrial weed control in gardens or along rail tracks (Woodburn, 2000;Kolpin et al, 2006;Ghanem et al, 2007;Botta et al, 2009). …”

Section: Special Focus On the Impact Of Glyphosate On Freshwater Micrmentioning

confidence: 99%

“…Glyphosate has long been assumed to be safe for the environment due to its supposed rapid biodegradation by soil microorganisms and/or the fact that it is tightly adsorbed by soil particles (Sprankle et al, 1975;Rueppel et al, 1977;Carlisle & Trevors, 1988;Pipke & Amrhein, 1988;Kolpin et al, 2006). The main degradation pathway appears to involve splitting the C-N bond to produce aminomethyl phosphonic acid (AMPA) (Rueppel et al, 1977).…”

Section: Glyphosate In the Environment: Degradation And Occurrence Inmentioning

confidence: 99%

Herbicide Contamination of Freshwater Ecosystems: Impact on Microbial Communities

Villeneuve¹,

Larroudé²,

Humbert³

2011

Pesticides - Formulations, Effects, Fate

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“…Existe preocupación respecto a los efectos adversos potenciales en la salud humana por exposición crónica ya que los humanos y otros animales pueden entrar en contacto con el glifosato y los aditivos presentes en las formulaciones comerciales a través de las prácticas rutinarias en agricultura (9), o a través de la cadena alimenticia (10), o a través de aguas contaminadas (11). Es así que tres estudios recientes de casos y controles han encontrado una asociación entre la exposición a herbicidas que contienen glifosato y el desarrollo de linfoma no Hodgkin (12,13).…”

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Citotoxicidad del glifosato en células mononucleares de sangre periférica humana

Martínez

Reyes

2007

biomedica

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Introducción. El glifosato es un herbicida de amplio espectro, no selectivo, utilizado comúnmente en agricultura para eliminar malezas. Los estudios que han evaluado la toxicidad del glifosato en animales y en ambiente muestran que las formulaciones comerciales son más tóxicas que el componente activo. Objetivos. Evaluar la toxicidad del glifosato grado técnico y de la formulación comercial Roundup® en células mononucleares de sangre periférica humana. Materiales y métodos. Células mononucleares de sangre periférica humana fueron expuestas a diferentes concentraciones de glifosato en grado técnico y en la forma de Roundup® por 24, 48, 72 y 96 horas. La citotoxicidad se evaluó mediante el método de exclusión con azul de tripano y reducción del reactivo sal sódica de (2,3-bis[2-metoxi-4-nitro-5-sulfofenil]-2Htetrazolio-5-carboxianilida) (XTT). Resultados. Ambas presentaciones del glifosato (grado técnico y Roundup®) fueron tóxicas para las células mononucleares de sangre periférica humana. Roundup® fue más citotóxico que el glifosato grado técnico, ya que se encontró que la concentración letal 50 (LC 50 ) analizada con el método de exclusión con azul de tripano a las 24 horas fue de 56,4 µg/ml de glifosato en la forma de Roundup® y de 1.640 mg/ml (1,64 µg/ml) para glifosato grado técnico. Conclusiones. Los resultados de este estudio in vitro confirman el efecto tóxico para las células humanas observado para el glifosato y sus preparaciones comerciales, y que estas últimas son más citotóxicas que el compuesto activo, lo que apoya la idea de que los aditivos presentes en las formulaciones comerciales juegan un papel crucial en la toxicidad atribuida a los herbicidas que contienen glifosato.Palabras clave: pruebas inmunológicas de citotoxicidad, herbicidas, células sanguíneas, supervivencia celular, azul de tripano, sales de tetrazolio. Cytotoxicity of the herbicide glyphosate in human peripheral blood mononuclear cellsIntroduction. Glyphosate is a broad-spectrum, non-selective herbicide and commonly used to eliminate weeds in agricultural and forest settings. Studies evaluating glyphosate toxicity in animals and environment show that commercial formulations of glyphosate are more toxic than the active component itself. Objectives. Technical grade glyphosate was compared with the commercial formulation Roundup® in their respective toxicities on human peripheral blood mononuclear cells. Materials and methods. Human peripheral blood mononuclear cells were exposed to different concentrations of glyphosate, either technical grade or in the form of Roundup for 24 h, 48 h, 72 h, and 96 h. Cytotoxicity was assayed by trypan blue dye exclusion method and reduction of (2,3-bis[2-methoxy-4-nitro-5-sulfophenyl]-2Htetrazolium-5-carboxyanilide inner salt) XTT reagent. Results. Both technical grade glyphosate and Roundup® formulation were toxic to human peripheral blood mononuclear cells. Cytotoxicity of Roundup® was higher than cytotoxicity of glyphosate, since the LC 50 (50% lethal concentration) determined by the trypan blue ex...

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Urban contributions of glyphosate and its degradate AMPA to streams in the United States

Cited by 224 publications

References 33 publications

Re-registration Challenges of Glyphosate in the European Union

Re-registration Challenges of Glyphosate in the European Union

Herbicide Contamination of Freshwater Ecosystems: Impact on Microbial Communities

Citotoxicidad del glifosato en células mononucleares de sangre periférica humana

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