“…The innovation ecosystem can be formed by partnerships which may include prospective user groups, companies, research institutions and universities, local authorities, etc.. The formation of these public-private-people partnerships (PPPP or 4Ps), also known as Quadruple Helix formations, can yield potential advantages, such as greater public involvement, transdisciplinary research, creativity and knowledge exchange [47], and also influence public affairs and policy innovation [48,49]. More specifically, in parallel with CS, LLs can also exercise different types of governance: (i) as an input for direct governance, LLs are used by policy makers to design, explore, experience, and refine new policies and regulations [40], or (ii) as a policy instrument for enriching regional innovation [50].…”