Urban Rural Comparisons of Polycystic Ovary Syndrome Burden among Adolescent Girls in a Hospital Setting in India

Balaji, Swetha; Amadi, Chioma; Prasad, Satish; Kasav, Jyoti Bala; Upadhyay, Vandana; Singh, Awnish Kumar; Surapaneni, Krishna Mohan; Joshi, Ashish

doi:10.1155/2015/158951

Cited by 44 publications

(38 citation statements)

References 18 publications

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“…Only a few researchers have studied the prevalence of PCOS in India and among those, most of the sampling was convenience based, which might not reflect the true status of PCOS prevalence in the community. A pilot cross-sectional study conducted in Tamil Nadu assessed young adolescent females and found a prevalence of 18 per cent for PCOS14. They also concluded that the proportion of PCOS was higher in urban women in comparison to the rural women.…”

Section: Epidemiology Of Pcos In Indiamentioning

confidence: 99%

Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India

Ganie

Vasudevan

Wani

et al. 2019

Indian Journal of Medical Research

161

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder predominantly affecting women of reproductive age. Clinical manifestations are diverse including hyperandrogenism, anovulation, infertility and increased risk of metabolic diseases besides psychosocial dysfunction. This review provides information on the problem of PCOS in India, its pathophysiology, genetics and an overview of current management options to instigate further research in this field. Prevalence of PCOS in India ranges from 3.7 to 22.5 per cent depending on the population studied and the criteria used for diagnosis. Abnormalities in leptin-adiponectin (adipocyte biology), oxidative stress and autoimmunity are among the mechanisms studied regarding pathogenesis of PCOS. Many candidate gene studies have shown associations with PCOS in various studies. Studies have consistently demonstrated the relationship between the well-known manifestation of hyperandrogenism among Indian PCOS women and the metabolic morbidities including insulin resistance, glucose intolerance and cardiovascular risk. Management of individual components of PCOS can be achieved by medications or surgical methods, though further clarification regarding pathogenesis of PCOS is needed to sharpen our therapeutic armamentarium.

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Section: Epidemiology Of Pcos In Indiamentioning

confidence: 99%

Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India

Ganie

Vasudevan

Wani

et al. 2019

Indian Journal of Medical Research

161

View full text Add to dashboard Cite

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“…Although the heritability of PCOS appears to be high, we should note that the proportion of heritability accounted for by the PCOS loci identified so far by current large-scale genome-wide association studies is <10%, which is not different from that observed with other complex genetic traits. In addition, and not reviewed in the present Views and Reviews series, we are also beginning to discover that epigenetic variations, including gene and histone methylation, and the action of histones, micro RNAs, RNA binding proteins, among others, also appear to play a role in determining the PCOS phenotype (1)(2)(3)(4)(5). Environmental determinants of PCOS and its phenotype are less well studied.…”

Section: Introductionmentioning

confidence: 95%

“…Cysts may be detectable by ultrasound. Other conditions that produce similar symptoms include adrenal hyperplasia, hypothyroidism, and high blood levels of prolactin [2].…”

Section: Introductionmentioning

confidence: 99%

An Updated Overview of Polycystic Ovary Syndrome

et al. 2019

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Polycystic ovary syndrome (PCOS), also known as Stein-Leventhal Syndrome, was first described in 1935. PCOS, which may also be referred to as polycystic ovary disease is the most common hormonal disorder found in premenopausal women. PCOS is the most common endocrine disorder in women of reproductive age and is the most common cause of infertility due to ovulation. A PCOS is an endocrine disorder which affects the adolescent girls. A PCOS is a condition in which a woman has an imbalance of female sex hormones. This may lead to changes in the menstrual cycle, cyst in the ovary, failure to conceive, and other health problems. It is a common health problem among teenagers and young women. It affects 5–10% of women in their reproductive years. These problems cause infertility. Two principal components to diagnose this syndrome are menstrual dysfunction and clinical or laboratory hyperandrogenism in which these items are used in clinical diagnosis. PCOS is a hormonal disorder that affects between 5% and 10% of women of reproductive age and remains the most enigmatic reproductive disorders. The most common symptoms of PCOS are obesity, acne, amenorrhea, irregular menstrual cycles, hirsutism, insulin resistance (IR), and high cholesterol. Due to the varied nature of PCOS and the large range of possible signs and symptoms, health personnel need a thorough knowledge of the disorder and its management. It is a major disorder characterized by elevated levels of male hormones (androgens), acne, and hirsutism. It can even cause IR, anovulation, and infertility on prolonging incidence of cysts. One of the treatments for PCOS is the use of synthetic medicine, which can help to treat PCOS but with side effects. However, many women who suffer from PCOS opt to use alternative medicine in conjunction with traditional medicine to improve their condition. There are some herbs that are very helpful in treating PCOS. Since PCOS is a curable disorder, it can be cured by the use of natural remedies or allopathic medication. There is a growing interest in herbal remedies or allopathic medication to cure the PCOS. There is a need to change the lifestyle management, diet to control the PCOS level. The natural remedies include treatment with phytoestrogenic and non-estrogenic herbs such as Licorice, Ginseng, Black cohosh, Dong, soy, evening primrose, honey, fenugreek, Schisandra root, and many other which are effective and safe. Many plants have been highly esteemed sources and have advantages which reduce PCOS and also having a hypoglycemic effect. In this review, an attempt has been made to study the use of natural remedy for the treatment of PCOS.

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“…It affects about 20% of the adolescent and adult female in Indian subcontinent. 1,2 PCOS is one of the most common cause of anovulation and infertility, it accounts to about 25 to 30% of the cause of infertility in women. 3 The relationship between hyperandrogenism and anovulation is complex.…”

Section: Introductionmentioning

confidence: 99%

Ovulation induction in polycystic ovarian syndrome - basics for gynecologist

Yadav¹

2021

Int J Reprod Contracept Obstet Gynecol

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Polycystic ovarian syndrome (PCOS) is the most common problem related to infertility among women. This review looked into the evidence and options available for ovulation induction. The management protocol and their respective efficacy was looked into during the write up of the review. Weight reduction, along with metformin therapy are the initial and efficient way to regain ovulation among obese female. This should be complemented by use of first line medicine like aromatase inhibitors and selective estrogen receptor modulators. The first line is effective in significant proportion of female to induce ovulation and increase live birth rate. However, for those not responding should initially undergo the use of gonadotropins and ovarian drilling. Finally, controlled ovarian stimulation and in vitro fertilization should be considered as it is an invasive, expensive and there are risks of ovarian hyperstimulation and multiple gestation.

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Urban Rural Comparisons of Polycystic Ovary Syndrome Burden among Adolescent Girls in a Hospital Setting in India

Cited by 44 publications

References 18 publications

Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India

Epidemiology, pathogenesis, genetics & management of polycystic ovary syndrome in India

An Updated Overview of Polycystic Ovary Syndrome

Ovulation induction in polycystic ovarian syndrome - basics for gynecologist

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