Urinary calcium excretion in children with monosymptomatic enuresis

Korzeniecka‐Kozerska, Agata; Porowski, Tadeusz; Wasilewska, Anna; Stefanowicz, Magdalena

doi:10.1007/s11845-014-1217-x

Cited by 7 publications

(11 citation statements)

References 29 publications

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“…Similarly, our study did not determine any differences in the pH levels of the group with voiding dysfunction when compared to the control group. The mean urine pH values of the groups in the Kozerska et al (16) study were around 6.3; thus, they were acidic as was determined in our study. This situation suggests that urine pH is more acidic in the pediatric age group compared to adults.…”

Section: Discussionsupporting

confidence: 76%

“…There was not any studies in the literature that compared voiding dysfunction and a control group in terms of urine density values. Kozerska et al (16) determined in their study that urine osmolality was higher in the enuretic group than in the control group. On the other hand, our study determined significantly lower urine density levels in the group with voiding dysfunction.…”

Section: Discussionmentioning

confidence: 94%

“…Studies in the literature have predominantly focused on the relationship of urinary calcium excretion with enuresis, hematuria, and urolithiasis. In a study that included 204 children, Kozerska et al (16) investigated the relationship between monosymptomatic enuresis (MNE) and urinary calcium excretion, and determined that children with MNE had higher urinary Ca+2 levels compared to controls in both spot and 24-hour urine samples. The same study determined no difference in urine pH values.…”

Section: Discussionmentioning

confidence: 99%

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Urine Density and pH: Do They Have a Relationship with Voiding Dysfunction?

Keskın¹,

Karaca²,

Aydoğdu³

et al. 2020

Terh

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Objective: The etiology of voiding dysfunction has garnered constant attention in the literature. Various factors such as UTI, bowel problems and constipation, negative attitudes of the social environment and the family, and genetics have been inspected and are still topics of investigation. UTI was found to have a strong association with pelvic wall dysfunction, constipation and lazy bowel syndrome, and voiding dysfunction. In this study we aimed to investigate the effects of urine pH and urine density studied in complete urinalysis on pediatric voiding dysfunction in order to contribute to the etiology of voiding dysfunction. Method: A total of 43308 children were included in the study. Based on results of screening, 42196 children without voiding dysfunction were included in Group 1 and 1112 children with voiding dysfunction were assigned to Group 2. Results of complete urinalysis of all identified children were scanned to obtain urine pH and density values. Differences between the two groups in terms of independent parameters (urine pH and density) were analyzed using Student's t-test. A p value<0.05 was considered statistically significant. Results: The group with voiding dysfunction was determined to have a statistically significantly higher mean age. There was no difference between the groups in terms of urine pH values. However, urine density values were statistically significantly lower in the group with voiding dysfunction. Conclusion: In general, children with voiding dysfunction are expected to have lower urine pH values, while urine density is not expected to show any differences. However, our study determined no differences in urine pH but detected lower urine density compared to the control group. Clearly, more advanced molecular or experimental prospective studies are required to explain this situation.

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Section: Discussionsupporting

confidence: 76%

Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Urine Density and pH: Do They Have a Relationship with Voiding Dysfunction?

Keskın¹,

Karaca²,

Aydoğdu³

et al. 2020

Terh

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“…"Urinary calcium excretion was significantly disturbed", this is what Korzeniecka-Kozerska concluded in a study in 2015 (13).…”

Section: Discussionmentioning

confidence: 57%

Assessment of idiopathic Hypercalciuria in Girls kids with Infrequent Voiding (Underactive Bladder)

et al. 2017

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Background: Hypercalciuria may be a sign of infrequent voiding; these symptoms may be treated if we get rid of hypercalciuria. Objectives: This paper is intended to get to the prevalence of hypercalciuria in girls (kids) with infrequent voiding. Methods: 80 patients with the index of infrequent voiding, who were admitted to Amir-Kabir hospital of Arak, and 80 children who were admitted without any particular disease just for a laboratory check were studied simultaneously. Urine sample (U/A-U/C), kidney, and bladder sonography was taken from both groups. Results: The prevalence of hypercalciuria in the normal group was 9.64% and in the case group was 53.18% (P = 0.003). Based on the chi-square test, hypercalciuria

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“…(9). Some authors found idiopathic hypercalciuria (IH) to be more common in children with PMNE than in children without nocturnal enuresis and for this reason they assume that IH could be one of the contributing pathophysiologic factor to PMNE (10,11,12). Considering 24 h-variations in urine calcium excretion, the diagnosis of hypercalciuria is most accurately determined from the urine collected for 24 h. This is usually difficult to achieve in children who have nocturnal enuresis.…”

Section: Introductionmentioning

confidence: 99%

Calciuria in children with primary mono-symptomatic nocturnal enuresis

Mulic

Muminovic³

et al. 2018

Sanamed

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Introduction: The prevalence of idiopathic hypercalciuria (IH) in healthy pediatric population ranges from 3.0% to 7.0%. There is insufficient data about IH in children with mono-symptomatic enuresis. The aim of this study was to examine calcium excretion in urine (UCa) in patients with primary mono-symptomatic nocturnal enuresis (PMNE). Methods: In patients with PMNE, aged 5 to 17 years, IH was determined in 24-h urine and from second morning spot urine. The completeness of the 24-h urine collections was estimated via measuring 24h-urine creatinine excretion (UCr) of 0.1-0.2 mmol/kg/24h. Results: Sixty patients with PMNE, 32 males and 28 girls, median age of 9 years were enrolled in the study. Only 41.7% patients successfully completed 24 h urine collection. IH, defined as 24-h UCa > 0.1 mmol/kg body weight, was diagnosed in 12% of the patients, while when defined as UCa/UCr > 0.8 mmol/mmol in children 5-7 years and > 0.6 mmol/mmol in those > 7 years, IH was 8.3% and 6.7% from 24h-urine and spot urine, respectively. Conclusion: Children and adolescents with PMNE are in risk of hypercalciuria. Therefore, it is useful to examine 24 hours of urine calcium excretion in these patients.

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Urinary calcium excretion in children with monosymptomatic enuresis

Cited by 7 publications

References 29 publications

Urine Density and pH: Do They Have a Relationship with Voiding Dysfunction?

Urine Density and pH: Do They Have a Relationship with Voiding Dysfunction?

Assessment of idiopathic Hypercalciuria in Girls kids with Infrequent Voiding (Underactive Bladder)

Calciuria in children with primary mono-symptomatic nocturnal enuresis

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