Urinary creatinine and creatine excretion in pigs in relation to body weight and nitrogen balance

Duggal, Surinder K.; Eggum, B. O.

doi:10.1002/jsfa.2740290805

Cited by 9 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…75 per day) and that of the pigs given the protein-free diet (61.20 mg/kgo. 75 per day) were comparable to those of Duggal & Eggum (1978) Aulstad (1970). There is also evidence (Duggal & Eggum 1978) that urinary creatinine excretion per unit bodyweight is lower at 25 kg than at 75 kg liveweight.…”

Section: Discussionsupporting

confidence: 74%

“…75 per day) were comparable to those of Duggal & Eggum (1978) Aulstad (1970). There is also evidence (Duggal & Eggum 1978) that urinary creatinine excretion per unit bodyweight is lower at 25 kg than at 75 kg liveweight. This latter relationship is relevant to the present study where the mean liveweights of the pigs on the two methods used to determine endogenous urinary metabolite excretion were not the same.…”

Section: Discussionsupporting

confidence: 74%

See 1 more Smart Citation

Endogenous urinary metabolite excretion in the growing pig

Moughan

Smith

Kies

1987

New Zealand Journal of Agricultural Research

View full text Add to dashboard Cite

Endogenous urinary total nitrogen (N) and urea N excretions in the growing pig were measured using either the protein-free or regression method. Eighteen entire male pigs (28 kg liveweight) were randomly and equally allocated between six levels of feeding of a barley diet. Mean daily urinary total N and urea N excretions were determined. The regression of urinary metabolite output on dietary N intake extrapolated to zero N intake gave endogenous urinary total N and urea N excretions of 144.6 and 51.5 mg/kgo. 75 per day, respectively. Corresponding values for six of the pigs subsequently given a protein-free diet for 11 days, with endogenous excretions calculated over the final six days, were 163.3 and 62.2 mg/kgo. 75 per day. The urinary creatinine excretion of the barley-fed pigs was not related to dietary N intake. Mean daily urinary creatinine excretion was 53.1 ± 3.3 mg/kgo. 75 whereas that for pigs given the protein-free diet was 61.2 ± 2.0 mg/kgo. 75 • Although endogenous urinary metabolite losses tended to be higher for pigs on the protein-free feeding regime, endogenous urea N and creatinine N were close to 0.40 and 0.14 of endogenous total N respectively for pigs fed either the protein-free or barley diet.

show abstract

Section: Discussionsupporting

confidence: 74%

Section: Discussionsupporting

confidence: 74%

Endogenous urinary metabolite excretion in the growing pig

Moughan

Smith

Kies

1987

New Zealand Journal of Agricultural Research

View full text Add to dashboard Cite

show abstract

“…Steger et al (1976) reported that the blood creatinine content of growing pigs is positively correlated with the weight of the animals. In agreement with this statement, Duggal & Eggum (1978) reported that the daily creatine and creatinine excretion of growing pigs was positively related to body-weight and to nitrogen retention. In addition, Murlin et al (1953) concluded from their results that high urinary creatinine excretion indicated high N utilization.…”

Section: Discussionsupporting

confidence: 68%

Effect of ileo-rectal anastomosis and post-valve T-caecum cannulation on growing pigs

et al. 1992

View full text Add to dashboard Cite

In a long-term study nine ileo-rectally anastomosed (IRA) and seven post-valve T-caecum (PVTC)-cannulated pigs were compared with six intact pigs with regard to different blood variables, sodium and potassium retention and weights of selected organs. After surgery, apart from urea and K measured 13 weeks post-surgery, there were no differences in the blood variables between the PVTC-pigs and intact pigs. In IRA-pigs concentrations of creatinine (P < 0.01), Na (P < 0 001), base excess (P < 0 001), pH (P < 0.01) and bicarbonate (P < 0,001) in blood were lower than those in intact pigs. At 13 weeks after surgery the blood K concentration in IRA-pigs was higher (P < 0.001) than that in PVTC-pigs or intact pigs. At 6 weeks after surgery the blood urea concentration in IRA-pigs was higher (P < 0.001) than that in intact and PVTC-pigs. At 13 weeks after surgery the urea concentration in PVTC-pigs was higher (P < 0,001) than those in IRA-pigs or intact pigs. The Na (P < 0.01 11 weeks after surgery) and (P < 0.05 and P < 0 01 5 and 11 weeks after surgery respectively) balances in IRA-pigs were lower than those in intact animals. Na retention was negative for IRA-animals 11 weeks after surgery. Na and K retentions were similar in PVTC-pigs and in intact pigs. The urinary: faecal excretion of Na differed slightly between PVTC-animals and intact animals. At 13 weeks after surgery there were no differences in organ weights between the PVTC-pigs and intact animals. In the IRA-pigs the weights of the liver (P 0.05), the kidneys (P > 0.05) and the adrenal glands were higher (P < 0.001) than those in the intact animals.

show abstract

“…To correct for differences in urine output, we evaluated the excretion of the marker relative to the output of creatinine. This metabolite is assumed to be excreted in a fairly constant rate relative to body weight (Duggal & Eggum, 1978). Its urinary concentration was determined colorimetrically at 492 nM following the Jaffé‐reaction (Creatinine liquicolor kit, Human Biochemica und Diagnostica mbH, Wiesbaden, Germany).…”

Section: Methodsmentioning

confidence: 99%

Fibre supplementation to pre‐weaning piglet diets did not improve the resilience towards a post‐weaning enterotoxigenic E. coli challenge

Hees

Maes

Millet

et al. 2020

Animal Physiology Nutrition

View full text Add to dashboard Cite

Dietary fibre (DF) is implicated in gastrointestinal health of weaned piglets, either through its physiochemical properties, through modulation of gut microbiota and (or) improved gut integrity. We aimed to study the effect of DF enriched supplemental diets fed to suckling piglets (‘creep feed’) on health and performance after weaning when challenged with an enterotoxigenic E. coli (ETEC). Seventy‐two piglets originating from 28 litters had been fed four creep diets, that is a low‐fibre control (CON); a diet containing 2% long‐chain arabinoxylans from wheat (lc‐AXOS) or 5% purified cellulose (CELL) or a diet containing the high fermentable and the low‐fermentable fibre source (i.e. 2% lc‐AXOS and 5% CELL). Upon weaning, piglets were individually housed and all fed the same diet. On days 7, 8 and 9, animals received an oral dose of ETEC (5 ml containing 107 to 108 CFU/ml). Besides growth performance, faecal and skin scores were recorded daily. Gut permeability was assessed by urinary excretion of Co‐EDTA prior and post‐ETEC challenge. Repeated measures in time were statistically evaluated with generalized linear mixed models. We used a binominal distribution for evaluating the faecal and skin scores. Feed intake and body weight gain did not differ between treatments (p > .05). Piglets on CELL decreased gain:feed ratio in week 2 + 3 week compared to CON (p = .035). Prior to ETEC challenge, gut permeability tended to increase for lc‐AXOS (p = .092). Moreover, lc‐AXOS as main effect increased intestinal permeability before ETEC challenge (p = .013), whereas the low‐fermentable fibre lead to elevated intestinal permeability after ETEC challenge (p = .014). The incidence of diarrhoea was higher for lc‐AXOS + CELL compared with lc‐AXOS (p = .036), while skin condition was unaffected. In conclusion, neither the high fermentable nor the low‐fermentable fibre source improved post‐weaning growth or gastrointestinal health of the piglets.

show abstract

Urinary creatinine and creatine excretion in pigs in relation to body weight and nitrogen balance

Cited by 9 publications

References 11 publications

Endogenous urinary metabolite excretion in the growing pig

Endogenous urinary metabolite excretion in the growing pig

Effect of ileo-rectal anastomosis and post-valve T-caecum cannulation on growing pigs

Fibre supplementation to pre‐weaning piglet diets did not improve the resilience towards a post‐weaning enterotoxigenic E. coli challenge

Contact Info

Product

Resources

About