Urinary Incontinence in Nulliparous Women and Their Parous Sisters

Buchsbaum, Gunhilde M.; Duecy, Erin E.; Kerr, Lindsey A.; Huang, Li‐Shan; Guzick, David S.

doi:10.1097/01.aog.0000187309.46650.b2

Cited by 61 publications

(28 citation statements)

References 22 publications

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“…In the Women's Health Initiative, almost one fifth of nulliparous women had some degree of prolapse [15]. Studies have established family history as a risk factor for other pelvic disorders such as urinary incontinence [16]. Could prolapse also have a genetic basis?…”

Section: Introductionmentioning

confidence: 99%

Family history as a risk factor for pelvic organ prolapse

et al. 2008

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The aim of this study was to determine whether a family history of prolapse and/or hernia is a risk factor for prolapse. A cohort of 458 women seeking gynecological care was classified as exposed (family history) or unexposed (without family history). We used chi2 to assess confounding and logistic regression to determine risk. Nearly half (47.3%) of the 458 participants reported a positive family history. Of these, 52.5% had prolapse. This was significantly higher than the 28.9% rate of prolapse in women without a family history (p<0.001). The crude risk ratio for family history of prolapse and/or hernia and prolapse was 1.8 (95% CI 1.4-2.3). After adjusting for vaginal deliveries, incontinence, and hysterectomy, the risk of prolapse was 1.4 (95% CI 1.2-1.8) times higher in women with a family history of prolapse and/or hernia. Heredity is a risk factor for prolapse. History taking should include both male and female family members.

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Section: Introductionmentioning

confidence: 99%

Family history as a risk factor for pelvic organ prolapse

et al. 2008

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“…9 Within each pair, one of the sisters was nulliparous while the other one had at least one vaginal delivery. All sister pairs in the study completed a comprehensive questionnaire that included information on demographics, past medical and obstetric history, and symptoms of urinary incontinence and pelvic organ prolapse.…”

Section: Methodsmentioning

confidence: 99%

Incontinence and pelvic organ prolapse in parous/nulliparous pairs of identical twins

Buchsbaum

Duecy

2008

Neurourology and Urodynamics

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“…Pairs of postmenopausal biological sisters were recruited from the general population in Western New York State and Northern Vermont between October 2002 and March 2005 as part of a study [7]. Within each pair, one of the sisters was nulliparous while the other had at least one vaginal delivery.…”

Section: Methodsmentioning

confidence: 99%

Is parity in the eye of the beholder?

Buchsbaum

Duecy

2007

Int Urogynecol J

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To investigate whether parity status can be predicted by physical examination and which findings are most predictive. A retrospective chart review of 75 postmenopausal nulliparous/parous sister pairs who underwent gynecological examination as part of a study. An examiner, blinded to parity status, predicted parity status based on physical findings recorded on 146 women. Parity status was correctly predicted for 84.9% of the women. Of the 22 women for whom parity prediction was incorrect, 11 were nulliparous and 11 parous. The physical findings most commonly used for prediction were presence or absence of abdominal striae, appearance of the cervical os, and condition of hymen. Absence of the hymen at 6 o'clock alone correctly predicted parity in 11 of 12 parous and 11 of 11 nulliparous women. Parity status can be predicted based on physical exam in the majority of women. Blinding of investigators to parity status may not be feasible.

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Urinary Incontinence in Nulliparous Women and Their Parous Sisters

Cited by 61 publications

References 22 publications

Family history as a risk factor for pelvic organ prolapse

Family history as a risk factor for pelvic organ prolapse

Incontinence and pelvic organ prolapse in parous/nulliparous pairs of identical twins

Is parity in the eye of the beholder?

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