Use of 2-octyl cyanoacrylate for skin closure of sternal incisions in cardiac surgery: observations of microbial barrier effects

Abstract

From the patient records reviewed in this study, it was found that the routine use of 2-octyl cyanoacrylate as an add-on measure to conventional sutures was associated with a significant reduction in infection rates for cardiovascular surgery patients.

Systematic review of the use of cyanoacrylate glue in addition to standard wound closure in the prevention of surgical site infection

“…Grauhan et al grouped deep and superficial wound infections together and reported a significant reduction in SSI in the cyanoacrylate glue‐sealed Donati sutures (two superficial infections) compared with the control group using subcuticular sutures alone (seven superficial infections +two deep infections) ( P < 0.05). In a large retrospective study of 1360 of patients undergoing cardiac surgery, Souza et al reported a significant reduction ( P < 0.001) in the incidence of SSI (superficial and deep) in the intervention group using additional cyanoacrylate glue (2.1%) compared with the control group (4.9%) …”

“…In a large retrospective study of 1360 of patients undergoing cardiac surgery, Souza et al reported a significant reduction (P < 0.001) in the incidence of SSI (superficial and deep) in the intervention group using additional cyanoacrylate glue (2.1%) compared with the control group (4.9%). 25 In paediatric surgery, Romero et al assessed the use of subcuticular suture and either cyanoacrylate glue or Steri-Strips ® in the closure of laparoscopic ports after laparoscopic appendectomy. 26 A single case of SSI occurred in the Steri-Strips ® group-no significant difference was identified in the incidence of SSI.…”

Comparison of conventional suturing and tissue adhesive (2-octyl cyanoacrylate) for port site skin closure in laparoscopic surgeries

“…11 Souza et al, found that routine use of topical adhesive for wound closure decreased the infection rates when used as an add-on measure to conventional sutures, with a significant reduction in infection rates for cardiovascular surgery patients. 12 Recently a comparative study conducted by Ando M et al, wound closure with staples was compared with 2-octyl cyanoacrylate. 8 out of 294 patients in the metal-staple group compared with none of 315 patients in the 2-octyl cyanoacrylate group acquired surgical site infections (SSIs) (p < 0.01).…”

Surgical Site Infections after Open Appendectomy and Effectiveness of Complex Approach to Their Prevention

“…Имеются также данные исследований об анти-микробных свойствах самого клея и эффективности совместного использования клея в комплексе мер профилактики ИОХВ [11,22].…”