Use of a Standard Fatty Meal as a Test for Fat Absorption

Penfold, W. A. F.; Keynes, W. Milo

doi:10.1097/00000658-197101000-00025

Cited by 22 publications

(6 citation statements)

References 5 publications

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“…In adults with pancreatic insufficiency, the determination of faecal fat has been defined as unnecessary [7] and alternatives to measuring faecal fat have been proposed [4,9,11]. However none of these methods seem suitable in children [10], in particular steatocrit and stool microscopy for fats are unreliable in our experience.…”

Section: Discussionmentioning

confidence: 96%

Monitoring steatorrhoea in cystic fibrosis

et al. 1994

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The aim of the study was the evaluation of the relationship between chemical fat analysis and some more rapid tests proposed to estimate steatorrhoea. Stool collections (72 h) were obtained on 32 occasions in 22 patients with cystic fibrosis and in seven healthy children. A very close relationship was found between faecal fat, as measured by standard chemical methods, and faecal energy (r = 0.95, P < 0.001). We conclude that the determination of faecal energy, easier to measure than faecal fat, can provide reliable information about the extent of steatorrhoea in cystic fibrosis.

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Section: Discussionmentioning

confidence: 96%

Monitoring steatorrhoea in cystic fibrosis

et al. 1994

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“…A Prosparol fat absorption test for malabsorption, by measuring the level of serum lipids after a fatty meal 20 29 30 , was found very suitable for geriatric patients. They were kept in bed for the period of examination to make it more comfortable for them and to make sure they did not take any meal or drink.…”

Section: Discussionmentioning

confidence: 99%

“…‐ These were examined in all patients by LKB ***8.600 Reaction Rate Analyser. In those with serum triglycerides (TG) below 0.88 mmol/l the fat absorption test 30 measuring the peak rises in serum esterified fatty acid (SEFA) and TG 20 29 30 was carried out.…”

Section: Methodsmentioning

confidence: 99%

Multiple Screening for Somatic Diseases among Long‐Term Psychogeriatric Patients

Brockbank

Brouckova

Giles

1978

Int J Clinical Practice

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Forty long-term psychogeriatric patients at Littlemore Hospital. Oxford, were subjected to multiple screening consisting of haematological examination, SMA, urine examination and a fat absorption test measuring the serum lipids after a fatty meal, which was found very suitable for geriatric patients. Some of the results were compared with those obtained by multiphasic screening for somatic diseases among elderly long-term psychiatric patients at Asgard Psychiatric Hospital, Norway. The normal values in the elderly are discussed. The authors are in doubt about the diagnostic and therapeutic value of regular screening in elderly patients, except for research purposes. They prefer individual examination, as and when required by the patient, to regular mass biochemical screening. They are also in favour of Polycythamia rubra vera Chronic respiratory diseases Dehydration with poor cerebral perfusion Chronic leukaemias (incl. thrombocytosis) Infection Metabolic/drug dyscrasias General Areas Covered Renal diseases (sec. hyperparathyroidism). Bone diseases Diabetes.

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“…The increase in serum or plasma particulate fat after an oral fat load has been the basis of several tests for fat malabsorption (Frazer and Stewart, 1937;Goldbloom, Blake, and Cameron 1964;Osmon, Zinn, and Wharton, 1957;Mullinger, 1968;Fosbrooke and Rudd, 1966;Penfold, 1967;Penfold and Keynes, 1971). In recent years, however, Stone and Thorp (1966) have shown nephelometry to be a far more convenient method for estimating particulate fat in serum or plasma than those used previously, and results correlate well with those of established methods (Buckley et al, 1970;Stone and Thorp, 1966;Stone et al, 1970).…”

mentioning

confidence: 87%

Changes in plasma nephelometry after oral fat loading in children with normal and abnormal small intestinal morphology.

Robards¹

1975

Archives of Disease in Childhood

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. Changes in plasma nephelometry after oral fat loading in children with normal and abnormal small intestinal morphology. A standardized oral fat load has been given to 66 children having duodenal or jejunal biopsy, and to 10 children presumed normal. The rise in plasma light scattering intensity (LSI) measured by nephelometry between the fasting and 2-hour postload level (0-2 hour) showed good correlation with the small intestinal morphology in patients suspected of having coeliac disease. In those who had had recurrent diarrhoea and gastroenteritis, the fat load test did not predict small intestinal morphology.Serial studies in 5 treated patients with malabsorption showed increase in the 0-to 2-hour LSI, with corresponding improvement of small intestinal morphology and clinical state.The increase in serum or plasma particulate fat after an oral fat load has been the basis of several tests for fat malabsorption (Frazer

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Use of a Standard Fatty Meal as a Test for Fat Absorption

Cited by 22 publications

References 5 publications

Monitoring steatorrhoea in cystic fibrosis

Monitoring steatorrhoea in cystic fibrosis

Multiple Screening for Somatic Diseases among Long‐Term Psychogeriatric Patients

Changes in plasma nephelometry after oral fat loading in children with normal and abnormal small intestinal morphology.

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