Use of Audiovisual Assisted Therapeutic Ambience in Radiotherapy (AVATAR) for Anesthesia Avoidance in a Pediatric Patient With Down Syndrome

Gutkin, Paulina M.; Donaldson, Sarah S.; Skinner, Lawrie; Callejas, Michelle; Cimino, Jaclyn; Lore, J.; Bush, Karl; Hiniker, Susan M.

doi:10.1016/j.adro.2020.100637

Cited by 2 publications

(1 citation statement)

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“…This unique approach has potential to minimize the burden of health care staff and health care cost needed in LMIC. [12] Advances in multimodal therapy for childhood cancer have led to more than 80% cure and survival rates for pediatric solid tumors but the adverse effects of therapy may cause debilitating events and sometimes poor quality of life beyond the primary disease process. The Childhood Cancer Survivor Study (CCSS) estimated that 1 in 5 childhood cancer survivors died after 30 years of survivorship with 1 in 10 deaths due to treatment-related factors.…”

Section: Discussionmentioning

confidence: 99%

Clinical profile of pediatric oncology patients treated with radiation therapy -- An institutional experience from Pakistan

Qureshi,

Ahmed,

Ali

et al. 2023

Preprint

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Background: This study aims to improve practices in pediatric radiation oncology in LMIC by sharing an institutional experience of radiation therapy (RT) for pediatric cancer at the Aga Khan University Hospital. Methods: All patients from January 2009 to December 2020 who received radiation therapy at Aga Khan University Hospital were included. Records were retrospectively reviewed from hospital information management system (HIMS) and radiation oncology information system were searched to identify children aged up to 19 years of age who received RT based on the pediatric protocol. Data was reviewed for frequencies and percentages were calculated for demographics, clinical characteristics, and treatment-related variables. Results: A total of 496 patients were offered RT for soft tissue and extra osseous sarcomas (n=115 patients, 23.2%), lymphomas and reticuloendothelial neoplasms (n=88 patients, 17.7%) and CNS and miscellaneous intracranial and intraspinal neoplasms (n=86 patients, 17.3%) and malignant bone tumors (n=77, 15.5% patients). The most common regions for radiation were head and neck (n=144, 29%) and CNS (n= 123, 24.3%). General anesthesia was used for radiation planning and/or execution of treatment in 122 (26.8%) patients. More than half the patients (n=261, 53.16%) received RT in the postoperative setting, 89 (18.13%) had RT as consolidative treatment. 30 (6.1%) leukemia patients received prophylactic radiation therapy and 103 (20.98%) received RT as a definitive treatment modality. Conclusions: Our study reinforces the use of radiation therapy in multidisciplinary management of different pediatric tumors. A multi-level pediatric cancer registry is required to assess the utilization of radiotherapy for different pediatric tumors. This will help in planning systems to cater to the needs of pediatric oncology management and survivorship.

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Section: Discussionmentioning

confidence: 99%