T he widely accepted cut-point for normal blood pressure (BP) in the office setting evolved over several decades, based on data derived from a variety of sources. The Actuarial Society of America was one of the first organizations to publish BP data on thousands of community residents, followed by other classic studies such as Framingham, Western Electric Company, Kaiser Permanente, and the Multiple Risk Factor Intervention Trial. 1,2 In every instance, BP readings were based on measurements taken by specially trained health professionals following guidelines for proper BP measurement. As a result of these and other population studies examining the association between different BP levels and cardiovascular outcomes, the importance of systolic and diastolic hypertension was recognized and an office BP of 140/90 mm Hg became the universally established cut-point for separating normal BP from hypertension.
Hypertension Is Not Defined by 140/90 in the "Real World"There are robust scientific data to support the use of 140/90 mm Hg to define hypertension in clinical practice guidelines. However, the guidelines do not take into account widely recognized problems associated with the quality of manual BP measurement in routine clinical practice. 3 More recent recommendations 4 for diagnosing hypertension clearly acknowledge that an increase in BP attributable to the "white coat response" is frequently associated with manual BP recordings performed in community-based practice. In recognizing this limitation of manual office BP, some guidelines have gone so far as to recommend that home BP and 24-hour ambulatory BP monitoring (ABPM) may need to be performed to obtain an accurate measure of a patient's BP status. The greater reliance on 24-hour ABPM and home BP in the diagnosis and management of hypertension is the result of numerous clinical outcome studies 5,6 that show that these measurement techniques are better predictors of cardiovascular events when compared to manual BP readings, even when manual readings are taken carefully in accordance with guidelines.However, most guidelines do not seem to have fully considered the impact conventional routine office BP might have on both the cut-point and ongoing management of hypertension as experienced by primary care physicians. In most instances, an office BP of 140/90 mm Hg is equated to a mean home BP or mean awake ambulatory BP of 135/ 85 mm Hg. However, this relationship has been based on BP readings carefully recorded in accordance with guidelines 4 for proper BP measurement (research-quality office BP readings) and may not reflect the BP obtained by doctors, nurses, and other health professionals in routine office practice.
Comparison of Casual and Research-Quality Manual BP MeasurementWhen the primary care physician records BP using a mercury or aneroid device, the resulting value frequently tends to be higher than what it would be if measurement guidelines were strictly adhered to. In a 1995 report from one of our centers, 7 BP data were obtained from 147 hypertensiv...