Use of bioelectric impedance analysis (BIA) in children with alterations of body water distribution

Body Composition and Water Compartment Measurements in Boys with Duchenne Muscular Dystrophy

“…Our results agree with the those of Bedogni et al 15,16 demonstrating a significant increase in the percentage of ECW and in the ECW/ICW ratio in the DMD group. Bedogni et al, 16 using deuterium oxide and sodium bromide dilution techniques, showed MFBIA to provide an accurate assessment of total body water in children with obesity, DMD, and juvenile rheumatoid arthritis. However, these investigators also found the coefficient of variation for ECW measurement to be highest in DMD, at 12.5%, and that DMD patients have a higher ECW/ ICW ratio when compared with controls.…”

“…However, these investigators also found the coefficient of variation for ECW measurement to be highest in DMD, at 12.5%, and that DMD patients have a higher ECW/ ICW ratio when compared with controls. 15,16 This group could not determine whether the elevation of this ratio was secondary to an increased fat mass that could not be determined by the measurements of skinfold thickness via calipers or if it was due to dystrophic lean muscle tissue with abnormally low ICW. Our study provides complimentary data to the studies by Bedogni et al 15,16 because of the addition of DEXA measures of FTM, which also determines the presence of intramuscular fat that would normally elude measurement by calipers.…”

“…15,16 This group could not determine whether the elevation of this ratio was secondary to an increased fat mass that could not be determined by the measurements of skinfold thickness via calipers or if it was due to dystrophic lean muscle tissue with abnormally low ICW. Our study provides complimentary data to the studies by Bedogni et al 15,16 because of the addition of DEXA measures of FTM, which also determines the presence of intramuscular fat that would normally elude measurement by calipers. If an increased fat mass were exclusively responsible for the increased ECW/ICW ratio found in DMD subjects compared with controls, we should have found relative increases in ECW/ICW ratio among able-bodied obese controls.…”

“…9 -12 Likely due to the underlying consequences of impaired cellular homeostasis, previous studies have determined that DMD patients have a lower percentage of total body water and higher extracellular water to intracellular water (ECW/ICW) ratio compared with controls. [13][14][15][16] However, these previous studies have not adequately measured fat mass and lean body mass. Hence, it has not been possible to discern whether this finding is due to the presence of increased fat mass in DMD subjects or a decreased amount of ICW in muscle cells.…”

Body composition by bioelectrical impedance analysis in children below 7 years old

“…에서 생체 전기저항법이 연구되었다 [8][9][10][11][12] 로 측정한 체지방 . BIA 률은 직접 측정법인 수중 체밀도법으로 측정한 결과와 높은 상관 성이 있고 13) 로 측정한 체지방률과 피지두께로 측정한 체지 , BIA 방률 사이에 매우 높은 상관성이 보고되었다 14,15) .…”