Use of dermal-fat grafts in the post-oncological reconstructive surgery of atrophies in the zygomatic region: clinical evaluations in the patients undergone to previous radiation therapy

Abstract

IntroductionGrafting of autologous adipose tissue can be recommended in some cases of facial plastic surgery. Rhabdomyosarcoma is a type of cancer that can also affect the orbit. Enucleation of the eye can cause atrophy of the corresponding hemiface and decreased orbital growth.Case reportWe report a case of a female patient with a medical history of surgical enucleation of the right eyeball, who had received rhabdomyosarcoma radiation therapy in her youth. The patient presented with a depression in the right zygomatic region. We took a dermal-fat flap from the abdominal region, which had been previously treated.ResultsThe surgical outcome, 48 hours, and much clearly 31 days after the surgery, revealed that the right zygomatic region had returned to its proper anatomical shape, although there were still signs of postoperative edema.DiscussionVery damaged tissues, like those exposed to radiation therapy, are generally not suitable for grafting of adipose tissue.ConclusionsIn the described case, we achieved a technically and aesthetically satisfying result despite the patient's medical history involving several perplexities about the use of autologous dermal-fat tissues, because of prior radiation therapy exposure. The clinical case shows that even a region exposed to radiation therapy can be a valid receiving bed for dermal-fat grafting.

Free Dermal Fat Graft for Reconstruction of Soft Tissue Defects in the Maxillofacial Region

“…Their grafts were survived with very good final cosmetic results. The current study is in agreement with the previous study done by Inchingolo et al 14 We thought that the graft survived even in the irradiate patients due to the dermal component of the graft and its proangiogenic properties with high ability of graft perfusion reestablishment.…”

“…This is due to the excessive release of cytokines that cause fibrosis and aberrant vascular tissue. 14 Despite these factors, studies have shown good results with FDFG in patients who have previously undergone radiation therapy. 14 In the current study, 2 patients with preauricular depression defects who underwent previous radiation therapy were treated with FDFG to reconstruct the soft tissue defects (Figure 4).…”

Successful use of a topical mixture with ozolipoile in the treatment of actinic ulcers

“…Reconstructive surgery could be indicated in areas deeply atrophic, following the radiotherapy. 15 , 16 …”

Biomechanical Behaviour of a Jawbone Loaded With a Prosthetic System Supported by Monophasic and Biphasic Implants

“…It's important to underline that the bone modification is a physiological process that combines the osteogenesis and the bone remodelling (13)(14)(15). In such cases where a guided bone regeneration is needed, the bone regeneration can be improved by using platelets concentrates (16,17), new generation of biomaterials, new surgical techniques (18)(19)(20)(21)(22)(23)(24)(25) or innovative devices.…”