Use of Desmopressin in Children With Inherited Platelet Dysfunctions Undergoing Adenotonsillar Procedures

García-Matte, Raimundo J.; Beltran, M.; Fonseca, Ximena; Barriga, Francisco; Wietstruck, Angélica; Zúñiga, Pamela

doi:10.1016/j.otoeng.2012.03.009

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…Despite a lack of RCTs investigating DDAVP in VWD, DDAVP has been shown to increase plasma VWF and factor VIII from two-fold to more than five-fold over baseline levels, with good or excellent results in most surgical adult patients [565][566][567] as well as children. 533,537,568,569 Although the use of DDAVP during pregnancy is controversial, 570 efficacy has been reported in obstetrical bleeding in women with bleeding disorders. 571 A literature and current practice survey performed by the European Haemophilia Therapy Strategy Board confirms that DDAVP can be used effectively to cover minor surgery and dental procedures in most VWD patients.…”

Section: Von Willebrand Disease Recommendationsmentioning

confidence: 99%

Management of severe perioperative bleeding

Kozek‐Langenecker

Ahmed

Afshari

et al. 2017

European Journal of Anaesthesiology

694

316

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: The management of perioperative bleeding involves multiple assessments and strategies to ensure appropriate patient care. Initially, it is important to identify those patients with an increased risk of perioperative bleeding. Next, strategies should be employed to correct preoperative anaemia and to stabilise macrocirculation and microcirculation to optimise the patient's tolerance to bleeding. Finally, targeted interventions should be used to reduce intraoperative and postoperative bleeding, and so prevent subsequent morbidity and mortality. The objective of these updated guidelines is to provide healthcare professionals with an overview of the most recent evidence to help ensure improved clinical management of patients. For this update, electronic databases were searched without language restrictions from 2011 or 2012 (depending on the search) until 2015. These searches produced 18 334 articles. All articles were assessed and the existing 2013 guidelines were revised to take account of new evidence. This update includes revisions to existing recommendations with respect to the wording, or changes in the grade of recommendation, and also the addition of new recommendations. The final draft guideline was posted on the European Society of Anaesthesiology website for four weeks for review. All comments were collated and the guidelines were amended as appropriate. This publication reflects the output of this work.

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