Use of glycoprotein IIb/IIIa receptor antagonist in prosthetic valve thrombosis

Giant left atrial appandage thrombus due to atrial fibrillation: successful treatment with warfarin

“…Glycoprotein2b/3a inhibitors may be considered as an alternative therapy for giant thrombus in LA/LAA. To our knowledge, glycoprotein2b/3a receptor blockers have been used in patients that have undergone percutaneous coronary intervention with a lower rate of bleeding and there are two reports on the successful use of glycoprotein2b/3a inhibitors in patients with mechanical prosthetic valve thrombosis [4,5]. Additionally, Yuce et.…”

Huge left atrial appendage thrombus in a patient with atrial fibrillation: Successful treatment with tirofiban

“…In our view, glycoprotein IIb/IIIa inhibitor infusion might provide an alternative treatment option in this problem. Besides there is an increasing and encouraging evidence regarding noncoronary applications of glycoprotein IIb/IIIa inhibitors such as prosthetic valve thrombus, pulmonary embolism, stroke and right atrial thrombus [3][4][5][6][7][8][9][10]. The potential use of glycoprotein IIb/IIIa inhibitors in these broad spectrum of non-coronary thrombotic conditions need to be tested with randomized studies.…”