Use of low-cost agro products as substrate in semi-continuous process to obtain carotenoids by Sporidiobolus salmonicolor

Colet, Rosicler; Urnau, Letícia; Bampi, Jaine; Zeni, Jamile; Dias, Bruna Bernar; Rodrigues, Eliseu; Jacques, Rosângela Assis; Luccio, Marco Di; Valduga, Eunice

doi:10.1016/j.bcab.2017.07.015

Cited by 25 publications

(8 citation statements)

References 41 publications

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“…Nevertheless, certain pigments are in a more advanced stage of scaling up. Some studies used SmF bioreactors, such as stirred tank and bubble column (Bühler et al, 2013;Rodrigues et al, 2014;Aruldass et al, 2015Aruldass et al, , 2016Colet et al, 2017;Sharma and Ghoshal, 2020). These more advanced studies are interesting, since they show the high potentialities of scaling up microbial pigments targeting a future industrial application.…”

Section: Modes Of Fermentation and Scale Of Productionmentioning

confidence: 99%

Agro-Industrial Residues: Eco-Friendly and Inexpensive Substrates for Microbial Pigments Production

Lopes

Ligabue-Braun

2021

Front. Sustain. Food Syst.

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Many commodities are abundantly produced around the world, including soybean, corn, rice sugarcane, cassava, coffee, fruits, and many others. These productions are responsible for the generation of enormous amounts of daily residues, such as cassava and sugarcane bagasses, rice husk, and coffee peel. These residues are rich sources for renewable energy and can be used as substrates for industrial interest products. Microorganisms are useful biofactories, capable of producing important primary and secondary metabolites, including alcohol, enzymes, antibiotics, pigments, and many other molecules. The production of pigments was reported in bacteria, filamentous fungi, yeasts, and algae. These natural microbial pigments are very promising because synthetic colorants present a long history of allergies and toxicity. In addition, many natural pigments present other biological activities, such as antioxidant and antimicrobial activities, that are interesting for industrial applications. The use of inexpensive substrates for the production of these metabolites is very attractive, considering that agro-industrial residues are generated in high amounts and usually are a problem to the industry. Therefore, in this article we review the production of microbial pigments using agro-industrial residues during the current decade (2010–2020), considering both submerged and solid state fermentations, wild-type and genetically modified microorganisms, laboratorial to large-scale bioprocesses, and other possible biological activities related to these pigments.

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Section: Modes Of Fermentation and Scale Of Productionmentioning

confidence: 99%

Agro-Industrial Residues: Eco-Friendly and Inexpensive Substrates for Microbial Pigments Production

Lopes

Ligabue-Braun

2021

Front. Sustain. Food Syst.

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“…In another work of the group using semicontinuous process to carotenoid production using different yeast the Sporidiobolus salmonicolor it was verified that the corn steep liquor substrate presented the highest levels of nitrogen and minerals (sodium, magnesium, iron, zinc, and copper), and the glycerol has the highest concentration of TOC. Which is important nutrient for the cell metabolism and cofactors for various enzymatic reactions [3,21]. Carotenoids concentration can be related to the culture medium composition as well as to the bioproduction system.…”

Section: Discussionmentioning

confidence: 99%

“…This may be related to the P. rhodozyma metabolism, a natural phenomenon that happens after high consumption of substrate. The increase in the pH level can be due to the ammonia formation as a consequence of amino acids degradation [21]. Colet et al [18] observed in fed-batch system an increase of pH value, regardless of the fed volume.…”

Section: Discussionmentioning

confidence: 99%

Fed-batch carotenoid production by Phaffia rhodozyma Y-17268 using agroindustrial substrates

2020

Biointerface Res Appl Chem

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This work aim the carotenoid bioproduction by the yeast Phaffia rhodozyma Y-17268 in a fed-batch bioreactor with different low-cost agroindustrial substrates (crude glycerol, corn steep liquor, and rice parboiling water). The maximum concentration of total carotenoid and cell productivity were 4118 µg/L (835 µg/g) and 0.05 g/L. h, respectively, with a feed volume of 75 mL every 12 h. The medium were composed of 100 g/L crude glycerol, 100 g/L corn steep liquor, and 20 g/L rice parboiling water at 25ºC, pHinitial 4.0, agitation rate of 250 rpm, aeration rate of 1.5 vvm and 96 h of bioproduction. 0.188 h-1 of maximum specific growth speeds (μmax) was obtained for the major carotenoid - (all-E)-β-carotene (75.9%). Thus, the yeast P. rhodozyma produced in a fed-batch bioreactor demonstrated a great potential to produce the β-carotene.

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“…Most of the studies on production of microbial biopigments utilized agroindustrial byproducts and their hydrolysates with commercially available nutrients, such as inorganic salts or purified organic extracts (Schneider et al, 2013;Goswami et al, 2015;Panesar et al, 2015;Cardoso et al, 2016;Liu and Zhu, 2017). Nonetheless, it has been demonstrated that it is possible to obtain microbial growth and biopigment production by elaborating a culture medium composed only of agroindustrial derivative products (Colet et al, 2017;Lin et al, 2019;Urnau et al, 2019;Kot et al, 2020). Because it is well known that agricultural wastes possess a variety of nutrients and micronutrients and that a wide number of microbes that synthesize biopigments are versatile organisms in terms of metabolic activity, it is of great relevance to this field that more studies based exclusively on agroindustrial byproducts need to be developed.…”

Section: Biopigmentsmentioning

confidence: 99%

Agroindustrial Byproducts for the Generation of Biobased Products: Alternatives for Sustainable Biorefineries

et al. 2020

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The integrated approach in biorefinery mainly involves the utilization of various agroindustrial byproducts such as raw materials for the production of several biobased products like biofuels, bioenergy, and other high-value chemicals. Biofuels are the backbone of biorefineries, however, production of value-added biomolecules such as biopigments, biopolymers, biosurfactants, and nutritional yeast has been attracting great attention. The production of these biomolecules using traditional approaches has been extensively studied in the last few years owing to their promising application in different industries such as chemical, food/feed, and pharmaceuticals for the development of novel products for mankind. Moreover, the production of such biomolecules using lignocellulosic, starchy, and some other agroindustrial byproducts is still not fully explored. Hence, there is a huge scope in the development of sustainable biorefining approaches to make the technology cost-effective. The lignocellulosic biomasses usually used in biorefineries are mainly composed of cellulose, hemicellulose, and lignin, whereas starchy materials, besides starch, usually contain, protein, lipids, and some micronutrients. The processing of these biomasses through successive steps like pretreatments, enzymatic hydrolysis, and fermentation is essentially required to obtained final biobased products. Considering certain bottlenecks of above-mentioned conventional biorefineries approaches, new technologies have been proposed for the improved pretreatment of biomass and efficient enzymatic hydrolysis in order to minimize the concentration of toxic inhibitors in resulting hydrolysate. In this review, we highlighted the different agroindustrial byproducts and their applications for the production of valuable biorefinery products.

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Use of low-cost agro products as substrate in semi-continuous process to obtain carotenoids by Sporidiobolus salmonicolor

Cited by 25 publications

References 41 publications

Agro-Industrial Residues: Eco-Friendly and Inexpensive Substrates for Microbial Pigments Production

Agro-Industrial Residues: Eco-Friendly and Inexpensive Substrates for Microbial Pigments Production

Fed-batch carotenoid production by Phaffia rhodozyma Y-17268 using agroindustrial substrates

Agroindustrial Byproducts for the Generation of Biobased Products: Alternatives for Sustainable Biorefineries

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