Use of low-dose recombinant factor VIIa in a pregnant patient with factor VII deficiency undergoing a minor surgery

Pınar, Hüseyin Ulaş; Başaran, Betül; Doğan, Rafi

doi:10.4103/2249-4472.155200

Cited by 2 publications

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Factor VII Deficiency and Pregnancy: Case Report and Review of Literature

Rohilla

Rai

Ahluwalia

et al. 2021

SN Compr. Clin. Med.

View full text Add to dashboard Cite

Inherited factor VII de ciency is an autosomal recessive coagulation disorder with broad range of bleeding manifestations. The association between bleeding and absolute factor VII level is poor. Usually, the bleeding is associated with FVII levels of less than 1% of the normal value. Factor VII de ciency is associated with prolongation of prothrombin time only with normal activated partial thromboplastin time.Approximately 66 pregnant women have been reported with factor VII de ciency so far in English literature.We hereby, report 2 cases along with the review of literature of Factor VII de ciency during pregnancy. Our patients were diagnosed to have factor VII de ciency after deranged coagulogram with factor VII level of < 1% and 17.1% respectively, however could be managed by fresh frozen plasma only in rst case and fresh frozen plasma & factor VII concentrate in second case successfully. Coagulogram is a simple, easily available, affordable and lifesaving investigation to detect this de ciency in pregnancy.

show abstract

Factor VII Deficiency and Pregnancy: Case Report and Review of Literature

Rohilla

Rai

Ahluwalia

et al. 2021

SN Compr. Clin. Med.

View full text Add to dashboard Cite

show abstract

Factor VII Deficiency and Pregnancy: A Case Report and Review of Literature

Rohilla

Rai

Ahluwalia

et al. 2021

Preprint

View full text Add to dashboard Cite

Inherited factor VII deficiency is an autosomal recessive coagulation disorder with broad range of bleeding manifestations. The association between bleeding and absolute factor VII level is poor. Usually, the bleeding is associated with FVII levels of less than 1% of the normal value. Factor VII deficiency is associated with prolongation of prothrombin time only with normal activated partial thromboplastin time. Approximately 66 pregnant women have been reported with factor VII deficiency so far in English literature. We hereby, report 2 cases along with the review of literature of Factor VII deficiency during pregnancy. Our patients were diagnosed to have factor VII deficiency after deranged coagulogram with factor VII level of < 1% and 17.1% respectively, however could be managed by fresh frozen plasma only in first case and fresh frozen plasma & factor VII concentrate in second case successfully. Coagulogram is a simple, easily available, affordable and lifesaving investigation to detect this deficiency in pregnancy.

show abstract

Use of low-dose recombinant factor VIIa in a pregnant patient with factor VII deficiency undergoing a minor surgery

Cited by 2 publications

References 5 publications

Factor VII Deficiency and Pregnancy: Case Report and Review of Literature

Factor VII Deficiency and Pregnancy: Case Report and Review of Literature

Factor VII Deficiency and Pregnancy: A Case Report and Review of Literature

Contact Info

Product

Resources

About