1984
DOI: 10.1016/b978-0-08-030764-0.50188-9
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Use of Monoclonal Antibodies to Keratin in Human Tumor Diagnosis

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Cited by 60 publications
(91 citation statements)
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“…However, there are circumstances in which the determination of CK 7 positivity is useful. We agree with Ramaekers et al (11) that CK 7 immunostaining can be extremely useful when the differential diagnosis between a prostatic carcinoma and a transitional cell carcinoma of prostate or other genitourinary organs is an issue. In the current study, all cases (0/18) of prostatic carcinoma were CK 7-negative, whereas the majority of cases (21/24) of transitional cell carcinoma were CK 7-positive.…”
Section: Discussionsupporting
confidence: 91%
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“…However, there are circumstances in which the determination of CK 7 positivity is useful. We agree with Ramaekers et al (11) that CK 7 immunostaining can be extremely useful when the differential diagnosis between a prostatic carcinoma and a transitional cell carcinoma of prostate or other genitourinary organs is an issue. In the current study, all cases (0/18) of prostatic carcinoma were CK 7-negative, whereas the majority of cases (21/24) of transitional cell carcinoma were CK 7-positive.…”
Section: Discussionsupporting
confidence: 91%
“…In the absence of results of other markers, the demonstration of CK 7 positivity alone has limited value in differential diagnosis of metastatic carcinoma (11). Its expression is often seen in the major categories of adenocarcinoma, including adenocarcinoma of the breast, lung, ovary, endometrium, thyroid, salivary gland, pancreas, and bile duct (21,25,26).…”
Section: Discussionmentioning
confidence: 99%
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“…Cytokeratin 7 (CK7) is a 5-kDa basic protein, which shows strong expression in different epithelia including the breast, upper gastrointestinal tract, endometrium, urinary bladder, pancreas, biliary tract, and lung. 32,33 CK7 expression was significantly more frequent in pulmonary adenocarcinoma and breast adenocarcinoma than adenocarcinoma of gastrointestinal (GI) origin. 34 In our case CK7 test expressed positivity.…”
Section: -102425mentioning
confidence: 99%