Use of phytotherapy in dentistry

Groppo, Francisco Carlos; Bergamaschi, Cristiane de Cássia; Cogo, Karina; Franz-Montan, Michelle; Motta, Rogério Heládio Lopes; Andrade, Eduardo Dias de

doi:10.1002/ptr.2471

Cited by 95 publications

(80 citation statements)

References 63 publications

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“…Many invitro studies have shown anti-inflammatory, antioxidant, anticarcinogenic, antimicrobial potential of various plant products [15]. Subramaniam et al, determined the effect of aqueous and organic extracts of three types of tea (green, oolong, and black tea) on the growth of S. mutans.…”

Section: Resultsmentioning

confidence: 99%

Effect of ACP-CPP Chewing Gum and Natural Chewable Products on Plaque pH, Calcium and Phosphate Concentration

Sultan

Telgi

Chaudhary

et al. 2016

JCDR

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Introduction: Numerous epidemiological studies have documented dental caries as the major public health problems throughout the world. It is gradually increasing in the underdeveloped and developing countries especially in children due to increasing popularity of refined sugars. Aim:The aim of the study was to evaluate the effect of natural chewable products (Tulsi, sesame seeds, fennel seeds, coconut) and ACP-CPP chewing gum on plaque pH, calcium and phosphate concentration. Materials and Methods:A randomized controlled trial, with a cross-over study design, was conducted. Ten subjects aged 15-17 years who agreed to refrain from oral hygiene practice for 48 hours prior to the sample collection were selected for the study.

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Section: Resultsmentioning

confidence: 99%

Effect of ACP-CPP Chewing Gum and Natural Chewable Products on Plaque pH, Calcium and Phosphate Concentration

Sultan

Telgi

Chaudhary

et al. 2016

JCDR

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“…The interest in naturally derived biological compounds that may have the potential to be used as therapeutics in medicine and dentistry is rising [13,31]. There are previous published studies on the activity of tea components against bacteria responsible for oral diseases.…”

Section: Microbiological Assays – Determination Of Minimum Inhibitorymentioning

confidence: 99%

Inhibitory activity of a green and black tea blend on Streptococcus mutans

Barroso

Ramalhete

Domingues³

et al. 2018

Journal of Oral Microbiology

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Through the years, tea consumption has been associated with good health, and some publications are related to oral health. The bioactive components of green tea are thought to be able to influence the process of caries formation through inhibition of proliferation of the streptococcal agent, interference with the process of bacterial adhesion to tooth enamel, and inhibition of glucosyl transferase and amylase; however, little is known about black tea and oral health. The aim of the present in-vitro study was to determine the inhibitory activity of a novel, patent-pending and proprietary blend of green and black tea aqueous extracts on Streptococcus mutans, a bacterium widely associated with plaque development and tooth decay. A minimum inhibitory concentration (MIC) of 12.5 mg/mL and a minimum bactericidal concentration (MBC) of 12.5 mg/mL was established against S. mutans, meaning that at concentrations of 12.5 mg/mL and higher, the proprietary tea blend is effective against the growth of S. mutans. This MIC concentration is lower than the ones reported in the literature for alcoholic black tea and green tea extracts tested separately. As a promising natural ingredient for oral health, this finding is a good indicator for the use of this proprietary blend of black and green tea water extracts.

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“…The toxicity of a dental material can be evaluated by in vitro tests in animals and humans. When a new product is developed, it is necessary to perform laboratorial tests with it, allowing safe clinical applications, and providing subsides for its use by health professionals and clinics proving its non-toxicity to tissue [11,12].…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of propolis in subcutaneous tissue of rats: a possible biomaterial for cavity cleansing

Almeida

Ferreira

Venâncio

et al. 2017

Rev. Odonto Ciênc. (Online)

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OBJECTIVE: The aim of this study was to histopathologically analyze, in subcutaneous connective tissue in rats, a propolis solution for cavity cleansing and its toxicity through hemolytic and Artemia franciscana tests. METHODS: Fifteen male rats were selected and randomly distributed in three experimental periods (07, 30 and 45 days), in which each animal received the four treatment groups in rounds: Group IPropolis I; Group II -Propolis II; Group III -Calcium Hydroxide Water and Group IV -2% Chlorexidine; the sides of the tube were the control group. The data were analyzed using descriptive statistics. The results showed, in terms of biocompatibility, that all materials presented a significant reduction of the inflammatory infiltrate and an increase of the thickness in the collagen fibers. It may be suggested, in decreasing order of biocompatibility, the use of following materials: calcium hydroxide-water, 2% chlorexidine, propolis I and propolis II. RESULTS: In the cytotoxicity test using A. franciscana, the propolis extract showed high toxicity when tested at concentrations and in the hemolytic activity test the propolis I extract showed greater activity than propolis II. CONCLUSION: The present study suggests the use of propolis as a cavity cleansing solution for shallow and medium cavities similar to 2% chlorexidine.Key words: Materials testing; Propolis; Dental cavity lining; Detergents Biocompatibilidade da própolis no tecido subcutâneo de ratos: um possível biomaterial de limpeza de cavidade RESUMO OBJETIVO: O objetivo deste estudo foi analisar histopatologicamente, em tecido conjuntivo subcutâneo de ratos, uma solução de própolis para a limpeza de cavidades e sua toxicidade através dos testes de hemólise e Artemia franciscana. METODOLOGIA: Foram utilizados 15 ratos machos, selecionados e distribuídos aleatoriamente em três grupos (n=5) em períodos experimentais (7, 30 e 45 dias), em que cada animal recebeu os quatro grupos de tratamento em forma de rodízio: Grupo I -Própolis I; Grupo II -Própolis II; Grupo III -Água de Hidróxido de Cálcio e Grupo IV -Clorexidina a 2%; as laterais do tubo foram o grupo controle. Os dados foram analisados pela estatística descritiva. RESULTADOS: Todos os materiais apresentaram uma redução significativa do infiltrado inflamatório e aumento da espessura das fibras colágenas. No teste de citotoxicidade de Artemia franciscana, o extrato de própolis apresentou alta toxicidade e no teste de atividade hemolítica o extrato de Própolis I mostrou-se mais ativo que o da Própolis II. CONCLUSÃO: O presente estudo mostrou a biocompatibilidade da própolis, sugerindo seu uso como solução de limpeza em cavidade cavidades rasas e médias semelhante à clorexidina a 2%.

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Use of phytotherapy in dentistry

Cited by 95 publications

References 63 publications

Effect of ACP-CPP Chewing Gum and Natural Chewable Products on Plaque pH, Calcium and Phosphate Concentration

Effect of ACP-CPP Chewing Gum and Natural Chewable Products on Plaque pH, Calcium and Phosphate Concentration

Inhibitory activity of a green and black tea blend on Streptococcus mutans

Biocompatibility of propolis in subcutaneous tissue of rats: a possible biomaterial for cavity cleansing

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