Use of Preoperative Magnetic Resonance Imaging for Breast Cancer

Arnaout, Angel; Catley, Christina; Booth, Christopher M.; McInnes, Matthew D. F.; Graham, Ian D.; Kumar, Vivek; Simos, Demetrios; Walraven, Carl van; Clemons, Mark

doi:10.1001/jamaoncol.2015.3018

Cited by 46 publications

(35 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…27 These results are similar to those from earlier retrospective studies from the USA. [24][25][26] Furthermore, a meta-analysis of the effect of MRI on the surgical management of ductal carcinoma in situ did not demonstrate any improvement in surgical outcomes.…”

Section: Discussionsupporting

confidence: 90%

“…Furthermore, adding breast MRI to the staging work-up may increase cost and patient anxiety and cause undue delays in definitive treatment. [24][25][26][27] While the standard policy is to complete a breast MRI examination and/or MRI-guided breast biopsy within 5 working days in pre-treatment evaluation at our institution, there have been reports in the literature that pre-operative breast MRI led to 22-30-day delays to surgery. 24,27 The objective of this study was to compare DCE MRI with BWBUS for the incremental detection of breast cancer beyond mammography in patients with biopsy-proven primary breast cancer.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Incremental cancer detection using breast ultrasonographyversusbreast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients

He¹,

Plaxco²,

Wei³

et al. 2016

BJR

View full text Add to dashboard Cite

Objective: To compare the incremental cancer detection rate (ICDR) using bilateral whole-breast ultrasonography (BWBUS) vs dynamic contrast-enhanced MRI in patients with primary breast cancer. Methods: A retrospective database search in a single institution identified 259 patients with breast cancer diagnosed from January 2011 to August 2014 who underwent mammography, BWBUS and MRI before surgery. Patient characteristics, tumour characteristics and lesions seen on each imaging modality were recorded. The sensitivity, specificity and accuracy for each modality were calculated. ICDRs according to index tumour histology and receptor status were also evaluated. The effect of additional cancer detection on surgical planning was obtained from the medical records. Results: A total of 266 additional lesions beyond 273 index malignancies were seen on at least 1 modality, of which 121 (45%) lesions were malignant and 145 (55%) lesions were benign. MRI was significantly more sensitive than BWBUS (p 5 0.01), while BWBUS was significantly more accurate and specific than MRI (p , 0.0001). Compared with mammography, the ICDRs using BWBUS and MRI were significantly higher for oestrogen receptorpositive and triple-negative cancers, but not for human epidermal growth factor receptor 2-positive cancers. 22 additional malignant lesions in 18 patients were seen on MRI only. Surgical planning remained unchanged in 8 (44%) of those 18 patients. Conclusion: MRI was more sensitive than BWBUS, while BWBUS was more accurate and specific than MRI. MRIdetected additional malignant lesions did not change surgical planning in almost half of these patients. Advances in knowledge: BWBUS may be a cost-effective and practical tool in breast cancer staging.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Incremental cancer detection using breast ultrasonographyversusbreast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients

He¹,

Plaxco²,

Wei³

et al. 2016

BJR

View full text Add to dashboard Cite

show abstract

“…24 Breslin et al 12 reported a higher number of traditional and advanced imaging tests among women with preoperative MRI, which increased over time (2005–2008). In their large study population (N=52,202) of commercially-insured younger women (<65 years), they concluded that advanced imaging was additive rather than replacing traditional imaging in the diagnostic workup of breast cancer.…”

Section: Discussionmentioning

confidence: 99%

Breast MRI in the Diagnostic and Preoperative Workup Among Medicare Beneficiaries With Breast Cancer

et al. 2016

View full text Add to dashboard Cite

Purpose We compared the frequency and sequence of breast imaging and biopsy use for the diagnostic and preoperative workup of breast cancer according to breast MRI use among older women. Methods Using SEER-Medicare data from 2004–2010, we identified women with and without breast MRI as part of their diagnostic and preoperative breast cancer workup and measured the number and sequence of breast imaging and biopsy events per woman. Results 10,766 (20%) women had an MRI in the diagnostic/preoperative period, 32,178 (60%) had mammogram and US, and 10,669 (20%) had mammography alone. MRI use increased across study years, tripling from 2005 to 2009 (9% to 29%). Women with MRI had higher rates of breast imaging and biopsy compared to those with mammogram and US or those with mammography alone (5.8 v 4.1 v 2.8; respectively). There were 4,254 unique sequences of breast events; the dominant patterns for women with MRI were an MRI occurring at the end of the care pathway. Among women receiving an MRI post-diagnosis, 26% had a subsequent biopsy compared to 51% receiving a subsequent biopsy in the sub-group without MRI. Conclusions Older women who receive breast MRI undergo additional breast imaging and biopsy events. There is much variability in the diagnostic/preoperative work-up in older women, demonstrating the opportunity to increase standardization to optimize care for all women.

show abstract

“…However, breast mri must be used with discernment given its limited specificity: very low in the earliest reports, but now generally accepted to be in the 60%-80% range [4][5][6][7][8][9][10][11] . Moreover, evidence is increasing that preoperative staging mri might be detrimental to patients, unnecessarily lengthening their investigation time because of the detection of additional nonspecific findings 13,14 and increasing the mastectomy rate with little reduction in re-excision and negative margins rates 15 . In that context, there has been a call for moderation with respect to routine orders for staging breast mri because no randomized controlled trial has yet demonstrated improved survival for women who undergo breast mri 16 .…”

Section: Introductionmentioning

confidence: 99%

Breast Magnetic Resonance Imaging: Are Those Who Need It Getting It?

et al. 2017

View full text Add to dashboard Cite

show abstract

Use of Preoperative Magnetic Resonance Imaging for Breast Cancer

Abstract: Preoperative breast MRI use has increased substantially in routine clinical practice and is associated with a significant increase in ancillary investigations, wait time to surgery, mastectomies, and contralateral prophylactic mastectomies.

Cited by 46 publications

References 48 publications

Incremental cancer detection using breast ultrasonographyversusbreast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients

Incremental cancer detection using breast ultrasonographyversusbreast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients

Breast MRI in the Diagnostic and Preoperative Workup Among Medicare Beneficiaries With Breast Cancer

Breast Magnetic Resonance Imaging: Are Those Who Need It Getting It?

Contact Info

Product

Resources

About