Mental health provider attitudes toward adopting evidence-based practice (EBP) are associated with organizational context and provider individual differences. Organizational culture and climate are contextual factors that can affect staff acceptance of innovation. This study examined the association of organizational culture and climate with attitudes toward adopting EBP. Participants were 301 public sector mental health service providers from 49 programs providing mental health services for youths and families. Correlation analyses and multilevel hierarchical regressions, controlling for effects of provider characteristics, showed that constructive culture was associated with more positive attitudes toward adoption of EBP and poor organizational climates with perceived divergence of usual practice and EBP. Behavioral health organizations may benefit from consideration of how culture and climate affect staff attitudes toward change in practice.Keywords organizational culture; climate; evidence-based practice; attitudes; implementation There is growing momentum to move evidence-based mental health interventions into realworld practice settings (Burns, 2003;Essock et al., 2003;Glisson, 2002;Goldman et al., 2001;Ringeisen & Hoagwood, 2002). Although there is a considerable literature on organizational factors associated with implementation of innovation in business settings (Frambach & Schillewaert, 2002;Klein, & Sorra, 1996) little research has examined organizational factors that may facilitate or hinder the implementation of evidence-based practice (EBP) in mental health settings. Research focusing specifically on the implementation of EBP in mental health settings can inform policymakers, administrators, providers, and researchers about factors that facilitate or hinder the implementation process. A better understanding of such factors can lead to the development of optimal implementation strategies tailored to specific organizational and service contexts.The study of attitudes toward EBP is in its infancy. The recently developed Evidence-Based Practice Attitude Scale (EBPAS; Aarons, 2004) The context into which EBPs are implemented is often complex and recently proposed models identify organizational factors that may facilitate or hinder the implementation of EBP and innovation in mental health settings (Aarons, 2005; Burns & Hoagwood, 2005). Studies have also identified a number of constructs thought to be important in effective implementation of innovation in organizations (Damanpour, 1991;Frambach & Schillewaert, 2002;Glisson, 2002) In particular, organizational culture and climate are two factors thought to influence attitudes toward adoption of innovation in general, and EBP in particular (Aarons, 2005). Management may decide to adopt an innovation but individual acceptance of an innovation is proposed to rely on both organizational and individual factors (Moore, 2002;Rogers, 1995) and to affect the degree to which EBPs are implemented with fidelity and competence. The present study focuses on th...