Use of Radiofrequency Ablation in Benign Thyroid Nodules: A Literature Review and Updates

Wong, Kai‐Pun; Lang, Brian Hung‐Hin

doi:10.1155/2013/428363

Cited by 49 publications

(42 citation statements)

References 61 publications

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“…Non-surgical treatment options were used to treat benign thyroid nodules. Those modalities have achieved great efficacy and mild complications [3,5,6,15,16].…”

Section: Discussionmentioning

confidence: 99%

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

Gong

Zhou

et al. 2017

Endocr J

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“…Non-surgical treatment options were used to treat benign thyroid nodules. Those modalities have achieved great efficacy and mild complications [3,5,6,15,16].…”

Section: Discussionmentioning

confidence: 99%

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

Gong

Zhou

et al. 2017

Endocr J

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“…However, the reported series of LA usually included patients with larger thyroid nodules and the series of RFA included patients with a higher cyst component [2]. Thus, the results are difficult to be compared [28]. To date, only one review including meta-analysis [29] and a more recent paper on a small case series [30] have reported direct comparisons between the two techniques with contradictory conclusions.…”

Section: Introductionmentioning

confidence: 99%

A comparison of laser with radiofrequency ablation for the treatment of benign thyroid nodules: a propensity score matching analysis

Pacella

Mauri

Cesáreo

et al. 2017

International Journal of Hyperthermia

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No significant differences were observed in the baseline characteristics between groups after propensity score matching adjustment. Mean nodule reduction at 6 and 12 months was -67 ± 19% vs. -57 ± 21% (p < 0.001) - 70 ± 19% vs. -62 ± 22% (p = 0.001) in LA group and in RFA group, respectively. Nodules with volume >30 mL had significantly higher percentage volume reduction at 6 and 12 months (-69 ± 19 vs. -50 ± 21, p = 0.001) and (-73 ± 18 vs. -54 ± 23 8, p = 0.001) in the LA group than in the RFA group, respectively. In both groups, operator's skills affected the results. Major complications occurred in 4 cases in each group (p = 0.116) Conclusions: LA and RFA showed nearly similar outcome but LA was slightly more effective than RFA in large nodules. Operator's skills could be crucial in determining the extent of nodule volume reduction regardless of the used technique.

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“…Many studies have reported improvements in neck discomfort and aesthetic symptoms after thyroid RFA. In the literature, aesthetic issues have been assessed by means of a score (generally from 1 to 4 or from 0 to 3) [12]. In our study, we used The aesthetic scale of ThyPRO, which did not reveal any improvement after thyroid RFA.…”

Section: Discussionmentioning

confidence: 99%

Quality of life in patients treated with radiofrequency ablation for thyroid nodules

Oddo¹,

Felix²,

Repetto³

et al. 2016

Res J Endocrinol Metab

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Background: Many studies have reported mean reductions in nodule volumes and described improvements in the sense of pressure and aesthetic symptoms after radiofrequency ablation. The aim of our study was to document changes in quality of life by means of a 13-scale questionnaire named ThyPRO in a cohort of patients treated with radiofrequency ablation for benign thyroid nodules. Moreover, we assessed the efficacy and safety of the procedure and correlations between efficacy and some features both of the treated nodules and of patients, and evaluated improvements in neck discomfort by means of a visual analogic scale. Methods: 32 patients with benign thyroid nodules were treated with radiofrequency ablation. We evaluated nodule volume, thyroid function and autoimmunity before and after procedures, adverse events during and after procedures, changes in neck discomfort by means of a visual analogic scale and changes in quality of life through the ThyPRO questionnaire at 1, 3, 6 12, 24 and 36 months. We sought correlations between response to radiofrequency ablation and some features of procedures and patients. We divided patients into 2 groups, according to their mean percentage of nodule volume reduction: group 1 (reduction >30%) and group 2 (reduction <30%) to evaluate whether ThyPRO questionnaire scores changed in patients in whom thyroid RFA was more effective. Results: At the last evaluation, nodule volume reduction was 45±9 in group 1, 11±9 in group 2 and 40±25% in the total population. We found a correlation between better volume reduction and greater patient age. Thyroid function and autoimmunity were not modified. Adverse events were few and mild. Visual analogic scale scores improved, though scores on the individual ThyPRO scales did not change, even in group 1. The general subjective impact of thyroid disease on quality of life improved from the 3rd month onwards. Conclusions: In our cohort of patients, quality of life, as evaluated through ThyPRO, did not improve after radiofrequency for benign thyroid nodules. In the literature, changes in quality of life in patients treated with radiofrequency ablation for thyroid nodules have been described in only one paper, while changes in quality of life assessed by means of ThyPRO have never been described.

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Use of Radiofrequency Ablation in Benign Thyroid Nodules: A Literature Review and Updates

Cited by 49 publications

References 61 publications

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

A comparison of laser with radiofrequency ablation for the treatment of benign thyroid nodules: a propensity score matching analysis

Quality of life in patients treated with radiofrequency ablation for thyroid nodules

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