Use of silastic tube and capillary sampling technic in the measurement of tissue PO2 and PCO2

Kivisaari, Jaakko; Niinikoski, J

doi:10.1016/0002-9610(73)90149-9

Cited by 70 publications

(16 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The normal sequences of change in PO, (Figure 2 ) are identical and the responses to systemic hyperoxia are generally similar to the findings of the earlier method. The advantages of the capillary sampling technique over continuous perfusion of the tonometer have been discussed elsewhere (Kivisaari & Niinikoski 1973 1.…”

Section: Discussionmentioning

confidence: 99%

“…For the measurements of tissue gas tensions the rahhits were lightly anesthetized with intramuscularly injected fentanyl citrate" and fluanison"' as described by Silver (1969). The ends of the tonometer were exposed through a small incision, and oxygen and carbon dioxide tensions in the healing hone were determined hy the method of Kivisaari & Niinikoski (1973).…”

Section: Oullltmentioning

confidence: 99%

See 1 more Smart Citation

Tissue Oxygen and Carbon Dioxide Tensions in Healing Rabbit Tibias

Kivisaari

Nlinikoski

1975

Acta Orthopaedica Scandinavica

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Oullltmentioning

confidence: 99%

Tissue Oxygen and Carbon Dioxide Tensions in Healing Rabbit Tibias

Kivisaari

Nlinikoski

1975

Acta Orthopaedica Scandinavica

Self Cite

View full text Add to dashboard Cite

“…A wound with an oxygen tension 5-20 mm Hg below the normal range 4 0 4 5 mm Hg is hypoxic [l2]. In vitro, 80 mm Hg was the maximum level of PO2 considered to be optimal for collagen synthesis and fi- [14,15] measured tissue gas tensions in vivo by means of a silastic tonometer implanted under the skin of rats to measure gas pressure. Subcutaneous tissue PO2 levels were increased to 600 mm Hg with exposure to HBO at 2 ATA.…”

Section: Introductionmentioning

confidence: 99%

Effects of different exposures of hyperbaric oxygen on ligament healing in rats

Ishii

Ushida

Tateishi

et al. 2002

Journal Orthopaedic Research

View full text Add to dashboard Cite

Hyperbaric oxygen (HBO) is a method of augmenting, intermittently, oxygen availability to tissues. We examined the effect of three different HBO exposures on the healing of experimentally induced ligament lacerations in the right hind limb of 44 male Wistar rats. Animals were divided into four groups after ligament injury: (a) control group, animals breathed room air a t 1 ATA (atmosphere absolute) in a hyperbaric chamber for 60 min; (b) HBO treatment at 1.5 ATA for 30 rnin once a day, (c) HBO treatment at 2 ATA for 30 min once a day, (d) 2 ATA for 60 rnin once a day. At 14 days post-ligament injury, we compared the ligaments of the four treatment groups for gross appearance, histology and expression of pro-a( I) mRNA by northern hybridization. Our results indicate that HBO was effective in promoting ligament healing compared to control (p < 0.01). Of these three exposures, HBO at 2 ATA for 60 min was the most effective, resulting in enhanced extra-cellular matrix deposition as measured by collagen synthesis.

show abstract

“…showed that the silastic tube induces a minimal foreign body reaction. Kivisaari & Niinikoski (1973) concluded that one of the main problems involved in measuring tissue gases by means of microelectrodes is the wide topographical variation of the PO, readings that normally occurs (Silver 1969). The advantage of the silastic tonometer is that it measures the average extracellular tissue PO, .…”

Section: Discussionmentioning

confidence: 99%

“…In earlier investigations the silastic tonometer has been used extensively in several tissues, such as human subcutaneous tissue , Kivisaari & Niinikoski 1973, human muscle (Cooke et al 1974), intestinal wall and peritoneal cavity in animals (Inberg et al 1974, Klossner et al 1974, canine lung (Havia & Niinikoski 1976) and canine heart (Havia & Niinikoski 1977).…”

Section: Discussionmentioning

confidence: 99%