In this paper, the mode coupling mechanism of tilted fiber Bragg gratings (TFBGs) is briefly introduced at first. And a general review on the fabrication, theoretical and experimental research development of TFBGs is presented from a worldwide perspective, followed by an introduction of our current research work on TFBGs at the Institute of Modern Optics, Nankai University (IMONK), including TFBG sensors for single-parameter measurements, temperature cross sensitivity of TFBG sensors, and TFBG-based interrogation technique. Finally, we would make a summary of the related key techniques and a remark on prospects of the research and applications of TFBGs.