Use or Misuse of Antibiotics in Pediatric Dentistry!!!

Abstract

In children, unjustified used of antibiotic is very common; specifically for ear and dental infections. Antibiotics are used in dentistry for two for most reasons: to control oral infection and to reduce systemic bacteremia. Antibiotics are universally prescribed by dentists, uses and mishandlings of these drugs should be accustomed to all committed clinicians. Physiological as well as the correct dosage of the medicine is equally important. In this article, the dental conditions and appropriate antibiotics are mentioned. The intracanal medicaments are mentioned. The appropriate use of antibiotics is advised for Pediatric age group. a) Absorption: Various host factors affect the absorption of drug. Example-existing surface area, gastric and duodenal pH, gastric emptying time, size of bile salt pool, bacterial colonization of gastrointestinal tract, presence and extent of underlying diseases influences drug absorption [4,5]. b) Distribution: Many factors should be taken intoconsideration -Body fat is lower in children so the distribution of fat-soluble drug is limited and half-life of drug would be shorter. Level of plasma proteins is lower, so level of free drug would be more. Blood brain permeability in children is also more [4,5]. c) Metabolism: Liver and kidney are the major organs liable for metabolism of drugs [4].