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In children, unjustified used of antibiotic is very common; specifically for ear and dental infections. Antibiotics are used in dentistry for two for most reasons: to control oral infection and to reduce systemic bacteremia. Antibiotics are universally prescribed by dentists, uses and mishandlings of these drugs should be accustomed to all committed clinicians. Physiological as well as the correct dosage of the medicine is equally important. In this article, the dental conditions and appropriate antibiotics are mentioned. The intracanal medicaments are mentioned. The appropriate use of antibiotics is advised for Pediatric age group. a) Absorption: Various host factors affect the absorption of drug. Example-existing surface area, gastric and duodenal pH, gastric emptying time, size of bile salt pool, bacterial colonization of gastrointestinal tract, presence and extent of underlying diseases influences drug absorption [4,5]. b) Distribution: Many factors should be taken intoconsideration -Body fat is lower in children so the distribution of fat-soluble drug is limited and half-life of drug would be shorter. Level of plasma proteins is lower, so level of free drug would be more. Blood brain permeability in children is also more [4,5]. c) Metabolism: Liver and kidney are the major organs liable for metabolism of drugs [4].

Introduction: Dental Fear (DF) and Dental Anxiety (DA) are the terms, used to symbolize early signs of Dental Phobia (DP). Dental anxiety in children due to sight of injection is the most common. Local anesthesia technique using camouflaged syringes has been tried to decrease anxiety and fear in children. This study was conducted by using most reliable scale is Venham Picture Test (VPT) and Face, Leg, Activity, Cry and Constability (FLACC) Behavioral Pain Assessment Scale to assess anxiety and fear in different groups of children being administered local anesthetic (LA) using either conventional or camouflaged syringe.Aim: To evaluate and compare dental anxiety and fear in children by using camouflaged and conventional syringe.Methodology: Total 80 children aged between 6-8 years were included. The appearance of Camouflage Syringe was child-friendly. Pictures of smiles, cars, cartoon characters, colourful fishes and sun were integrated in the design of Camouflage Syringe. The trial had two groups-Camouflaged (CaS) and conventional syringe (CoS) group. Inferior alveolar nerve block was administered in both the groups using the allocated type of syringes. VPT and FLACC scales were used.Results: A total of 52 male and 28 female children were integrated in the study. Comparison of the Venham picture test score and FLACC score in terms of [Mean (SD)] (SD -standard deviation) was done amongst both the groups using unpaired t-test. The FLACC score [Mean (SD)] for group I and II were, 2.53 (0.5) and 1.48 (0.5) respectively. The [Mean (SD)] for group I and Group II of VPT was 6.40 (1.2) and 3.85 (1.0) respectively, while that for FLACC was .53 (0.5) and 1.48 (0.5) respectively. Conclusion:The anxiety level of Female children was significantly higher than male children. By using Camouflaged Syringe, Fear and anxiety were significantly reduced.