Objective. The purpose of this study was to evaluate the effect of premicturitional bladder volume (V 1 ) on postvoid residual urine volume (V 2 ) measurements and to assess the ideal V 1 for an accurate V 2 determination. Methods. Twenty-five healthy men without any urinary symptoms constituted the study group. Measurements by transabdominal ultrasonography for V 1 and V 2 were performed for each subject at 3 different phases, each of which was preceded by oral intake of 1000 mL of water and accompanied by "mild," "moderate," and "severe" sensations of micturition, respectively. Results. Mean ± SD V 1 and V 2 during the first, second, and third phases were 117.7 ± 70.3 and 1 ± 1, 356.2 ± 112.3 and 11.5 ± 12 and 639.6 ± 171.8 and 58.8 ± 35.2 mL, respectively. With 50 mL as the cutoff value for a pathologic V 2 , 15 (60%) men had V 2 in the third phase exceeding this value, whereas the same rate was calculated as 0% for either of the first 2 phases. No patient with V 1 of less than 540 mL had V 2 of greater than 50 mL. Conclusions. Postvoid residual urine volume measurements with an uncomfortably full bladder result in high false-positive postmicturitional residue values even in healthy young men. We strongly advise that V 1 measurements of the bladder be performed before V 2 measurements and that V 2 not be measured if V 1 is greater than 540 mL. Key words: bladder; residual volume; ultrasonography. he accurate determination of postvoid residual urine (PVR) volume (V 2 ) is an important factor for diagnosing voiding dysfunction and for making a decision regarding the treatment options in the management of benign prostatic hyperplasia.