2020
DOI: 10.1161/circimaging.119.010356
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Usefulness of Cardiac Magnetic Resonance Imaging in Aortic Stenosis

Abstract: The objective of this review is to provide an overview of the role of cardiac magnetic resonance (CMR) in aortic stenosis (AS). Although CMR is undeniably the gold standard for assessing left ventricular volume, mass, and function, the assessment of the left ventricular repercussions of AS by CMR is not routinely performed in clinical practice, and its role in evaluating and quantifying AS is not yet well established. CMR is an imaging modality integrating myocardial function and disease, which could be partic… Show more

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Cited by 56 publications
(50 citation statements)
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“…Also, the invasive measurements of left ventricle and aortic pressures can give a functional AVA estimation by the Gorlin equation or by the Hakki's simplified version of the formula, during left heart catheterization. Finally, planimetric and continuity equationderived AVA obtained by cardiac magnetic resonance (CMR) showed good correlation with TTE and TOE [13]. All these quantification techniques can be useful in the case of poor acoustic window or inadequate Doppler alignment, but none of them is able to give a comprehensive assessment of AS severity grade in the low-flow setting.…”
Section: Other Imaging Techniquesmentioning
confidence: 99%
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“…Also, the invasive measurements of left ventricle and aortic pressures can give a functional AVA estimation by the Gorlin equation or by the Hakki's simplified version of the formula, during left heart catheterization. Finally, planimetric and continuity equationderived AVA obtained by cardiac magnetic resonance (CMR) showed good correlation with TTE and TOE [13]. All these quantification techniques can be useful in the case of poor acoustic window or inadequate Doppler alignment, but none of them is able to give a comprehensive assessment of AS severity grade in the low-flow setting.…”
Section: Other Imaging Techniquesmentioning
confidence: 99%
“…From this point of view, the myocardial tissue characterization provided by CMR can add useful information to understand the nature of LV dysfunction; AS is often associated to late gadolinium enhancement (LGE), usually with a midwall scar, differently from the typical pattern of myocardial infarction. Moreover, the presence of midwall LGE in AS has been associated to a significantly higher rate of 30-day mortality [13]. Although the current guidelines for heart valve disease management [1,2] do not recognize a role to CMR in the diagnostic workup of AS, this technique might provide adjunctive data to predict the possible benefits of AVR.…”
Section: Other Imaging Techniquesmentioning
confidence: 99%
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“…However, assessment of ECM composition and microcalcification is constrained by limited spatial resolution in both modalities. CT is the primary imaging modality to assess calcification burden (90)(91)(92), owing to its excellent spatial resolution and high discriminatory power to detect calcification (92) but not other tissue components. Direct evaluation of tissue changes would be the ideal diagnostic tool to monitor disease development and progression and to determine end points for evaluation of therapeutic interventions (93).…”
Section: Imaging Valvular Fibrosismentioning
confidence: 99%
“…Temporal resolution is high and the spatial resolution allows for the detection of leaflet thickening and macrocalcification. Due to the superior acoustic window, transesophageal echocardiography may be used to characterize calcification distribution ( 90 ). However, assessment of ECM composition and microcalcification is constrained by limited spatial resolution in both modalities.…”
Section: Imaging Valvular Fibrosismentioning
confidence: 99%