Usefulness of Intraductal Ultrasonography in the Diagnosis of Cholangiocarcinoma and IgG4-Related Sclerosing Cholangitis

Abstract

The technique of intraductal ultrasonography (IDUS) of the bile duct with a thin-caliber probe and a ropeway system has provided excellent images of the bile duct and periductal structures and is an easy transpapillary approach. In addition, once the guide wire is inserted into the bile duct, IDUS and transpapillary biopsy after endoscopic retrograde cholangiopancreatography can be performed in a single session. Here, we review the usefulness of IDUS in the diagnosis of cholangiocarcinoma and IgG4-related sclerosing cholangitis.

Immunoglobulin G4–Related Sclerosing Cholangitis Mimicking Hilar Cholangiocarcinoma Diagnosed With Following Bile Duct Resection: Report of a Case

“… 23 Therefore, transpapillary biopsy may not be useful for the diagnosis of IgG4-SC, even with IgG4 immunostaining. 23 – 25 …”

Endoscopic diagnosis of cholangiocarcinoma: From endoscopic retrograde cholangiography to bile proteomics

“…Signs of malignancy are hypoechoic masses with irregular margins and inhomogeneous low-echo areas invading the surrounding tissue [29]. IDUS is reported to be more accurate than forceps biopsies and cytology to diagnose CCA [30,31].…”

Colangiopancreatografia retrógrada endoscópica versus ultrassom endoscópico no diagnóstico histológico da estenose biliar maligna: revisão sistemática e metanálise

“…O diagnóstico não invasivo pode ser realizado através de marcadores tumorais séricos e exames de imagens, como: ultrassom (US), colangiorressonância magnética (CRMN), cintilografia por emissão de pósitrons (PET-scan) e tomografia computadorizada (TC); ou métodos endoscópicos, tais como: colangiopancreatografia retrógrada endoscópica (CPRE), ultrassom endoscópico (ECO-EDA), colangioscopia, endomicroscopia confocal, tomografia de coerência óptica (OCT) e ultrassom intraductal (IDUS) (Crone-Munebrock et al, 1990a;Pasanen et al, 1993;Fritscher-Ravens et al, 2004;Sakai et al, 2007;Charbel e Al-Kawas, 2011;Victor et al, 2012;Nakazawa et al, 2012;Khan et al, 2013;Gabbert et al, 2013).…”