Usefulness of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as predictors of severity on Fournier fasciitis of the Hospital General de México Ó?Dr. Eduardo LiceagaÓ�

Abstract

Background: Fournier fasciitis (FF) severity is traditionally assessed by the Fournier gangrene severity index (FGSI), as it is an internationally accredited index, which consists of some clinical and laboratory parameters. However, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have shown to be useful as predictors of severity in different septic and ischemic processes, and a full blood count is sufficient for its application. Objectives: The objectives of this study were to determine if there is a correlation between FF severity measured by NLR and PLR, and the severity measured by the FGSI scale. Materials and methods: We conducted a retrospective, observational, and analytical study to evaluate the usefulness of the NLR and PLR as indicators of severity on Fournier fasciitis. Results: We included 45 cases treated at Hospital General de México "Dr. Eduardo Liceaga", from 2010 to 2016. Forty cases were of anorectal origin and five of them of urological origin. The severity assessment scale was set for FGSI at 9 points, NLR at 7 points, and PLR at 140 points. About 60% of cases deemed severe by NLR, resulted in an FGSI score lower than 9, p = 0.547, without statistical significance. About 72% of cases diagnosed as severe by PLR, yielded an FGSI score lower than 9, p = 0.613, without statistical significance. Conclusions: Additional studies would be required to confirm or rule out these results.

The Prognostic Role of Neutrophil-Lymphocyte Ratio in Fournier Gangrene Patients

“…One of the most commonly used parameter is the neutrophil-lymphocyte ratio (NLR) [11] . Findings regarding its potential use in predicting the prognosis of Fournier gangrene patients have been reported, however more investigations are still needed to determine its value as a biomarker [12][13][14] . Therefore, we aimed to evaluate the role of neutrophillymphocyte ratio as a prognostic marker for Fournier gangrene patients.…”