Usefulness of Sonography for Diagnosis of Siliconomas Mimicking Metastatic Lymphadenopathy on Computed Tomography

Kim, Jeong Rye; Chang, Moo Hwan; Kim, You-Me

doi:10.7863/ultra.34.1.167

Cited by 4 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Affected patients usually describe single or multiple indurated, palpable, or painful nodules or masses in the breast, with a range of sizes. [72][73][74][75] Ipsilateral, or rarely contralateral, regional lymph nodes (internal mammary chain, axillary, and supraclavicular) may also be affected. 72,74,76,77 Imaging Silicone granulomas are often associated with implant rupture.…”

Section: Clinical Featuresmentioning

confidence: 99%

“…[72][73][74][75] Ipsilateral, or rarely contralateral, regional lymph nodes (internal mammary chain, axillary, and supraclavicular) may also be affected. 72,74,76,77 Imaging Silicone granulomas are often associated with implant rupture. 78 On mammography, siliconomas typically exhibit irregular or circumscribed high-density masses.…”

Section: Clinical Featuresmentioning

confidence: 99%

“…On mammography, siliconomas typically exhibit irregular or circumscribed high-density masses. The US characteristics of siliconomas are variable, encompassing hypoechoic or anechoic masses that resemble cysts, as well as echogenic masses with the typical “snowstorm” appearance 74,79 . Siliconomas on MRI demonstrate a low signal on T1, a high signal on T2, and silicone selective sequences without or variable enhancement 46,76,80 …”

Section: Siliconomamentioning

confidence: 99%

See 2 more Smart Citations

The Spectrum of Non-neoplastic Changes Associated With Breast Implants

Marques-Piubelli,

Lyapichev,

FNU

et al. 2024

American Journal of Surgical Pathology

View full text Add to dashboard Cite

Breast implant-associated anaplastic large cell lymphoma has been recognized as a distinct entity in the World Health Organization classification of hematolymphoid neoplasms. These neoplasms are causally related to textured implants that were used worldwide until recently. Consequently, there is an increased demand for processing periprosthetic capsules, adding new challenges for surgeons, clinicians, and pathologists. In the literature, the focus has been on breast implant-associated anaplastic large cell lymphoma; however, benign complications related to the placement of breast implants occur in up to 20% to 30% of patients. Imaging studies are helpful in assessing patients with breast implants for evidence of implant rupture, changes in tissues surrounding the implants, or regional lymphadenopathy related to breast implants, but pathologic examination is often required. In this review, we couple our experience with a review of the literature to describe a range of benign lesions associated with breast implants that can be associated with different clinical presentations or pathogenesis and that may require different diagnostic approaches. We illustrate the spectrum of the most common of these benign disorders, highlighting their clinical, imaging, gross, and microscopic features. Finally, we propose a systematic approach for the diagnosis and handling of breast implant specimens in general.

show abstract

Section: Clinical Featuresmentioning

confidence: 99%

Section: Clinical Featuresmentioning

confidence: 99%

Section: Siliconomamentioning

confidence: 99%

See 1 more Smart Citation

The Spectrum of Non-neoplastic Changes Associated With Breast Implants

Marques-Piubelli,

Lyapichev,

FNU

et al. 2024

American Journal of Surgical Pathology

View full text Add to dashboard Cite

show abstract

“…Extravasation of silicone after extracapsular rupture results in silicone uptake in the breast lymphatics and lymphatics throughout the body. Even without obvious extracapsular rupture, silicone may leak out of the implant on a microscopic level, a phenomenon known as gel bleeding (33). Silicone-laden nodes undergo a granulomatous reaction and are typically enlarged, are FDGavid at PET/CT, and rarely enhance with CT contrast material (Fig 14) (33).…”

Section: Differential Diagnosismentioning

confidence: 99%

“…Even without obvious extracapsular rupture, silicone may leak out of the implant on a microscopic level, a phenomenon known as gel bleeding (33). Silicone-laden nodes undergo a granulomatous reaction and are typically enlarged, are FDGavid at PET/CT, and rarely enhance with CT contrast material (Fig 14) (33). At US, however, silicone lymphadenopathy demonstrates a hyperechoic and characteristic snowstorm appearance (Fig 14).…”

Section: Differential Diagnosismentioning

confidence: 99%

Internal Thoracic Lymphadenopathy in Breast Cancer

2017

View full text Add to dashboard Cite

The internal thoracic (IT) nodal basin is a first-echelon drainage pathway in the breast, accounting for up to a quarter of its lymphatic drainage, primarily from the deep structures of the breast. The presence of internal thoracic node (ITN) metastases upstages the breast cancer (BC) patient to a minimum of clinical stage III disease. Medial tumors, deep tumors, young age, axillary nodal metastases, tumors of a high nuclear grade, lymphovascular invasion, and triple-negative hormone receptor status are predisposing factors for ITN metastases from primary BC. It has been observed that medial tumors carry a worse prognosis than lateral tumors when all other factors are equal, indicating that understaging of ITN has a significant impact on patient outcomes. Despite the established prognostic significance of IT adenopathy in BC, this nodal basin is not routinely staged due to the difficulty in accessing it and due to the controversy regarding its management. Since the initial ITN studies in the 1960s, improvement in imaging techniques and the availability of minimally invasive biopsy techniques have fueled renewed interest in ITNs and their clinical significance in BC. Radiologists who image and diagnose BC can offer more accurate staging assessments by consistently evaluating the IT nodal chain in the BC patient. In this article, the authors discuss current knowledge of the ITNs in BC and review ITN anatomy. The imaging appearance of pathologic ITNs using various modalities, potential mimics of IT adenopathy, and image-guided sampling techniques are described. A succinct discussion of the clinical management of ITN-positive BC and its challenges is also included. RSNA, 2017.

show abstract