Using an artificial neural network for the evaluation of the parameters controlling PVA/chitosan electrospun nanofibers diameter

Abstract

The purpose of this study was to investigate the validity of an artificial neural network (ANN) method in the prediction of nanofiber diameter to assess the parameters involved in controlling fiber form and thickness. A mixture of polymers including poly(vinyl alcohol) (PVA) and chitosan (CS) at different ratios was chosen as the nanofiber base material. The various samples of nanofibers were fabricated as training and testing datasets for ANN modeling. Different networks of ANN were designed to achieve the purposes of this study. The best network had three hidden layers with 8, 16 and 5 nodes in each layer, respectively. The mean squared error and correlation coefficient between the observed and the predicted diameter of the fibers in the selected model were equal to 0.09008 and 0.93866, respectively, proving the efficacy of the ANN technique in the prediction process. Finally, three-dimensional graphs of the electrospinning parameters involved and nanofiber diameter were plotted to scrutinize the implications.

Study on porosity of electrospun nanofiber membrane by neural network

“…Between the input layer and the output layer is hidden layer, hidden layer and the number of nodes in each layer determines the complexity of the neural network. In recent years, the use of neural networks on the porosity has attracted the interest of many scholars [1,[10][11][12]. In this paper, the influence of electrospinning process parameters on the porosity of nanofiber membranes is studied by means of neural network.…”

Biocompatibility and nanostructured materials: applications in nanomedicine

“…Their use in diverse areas has been vastly explored in recent years, offering great advantages over conventional materials. In particular, the engineered nanomaterials have been widely investigated for the biomedical applications, including development of new diagnostic tools such as nanobiosensors and precise imaging modalities, novel therapeutics based on targeted drug delivery systems, and scaffolds for tissue engineering (Chang 2014, Karimi et al 2015, Ketabchi et al 2016, Naghibzadeh and Adabi 2014. Due to the increasing usage of nanomaterials in various fields of science and technology, the concerns have been emerged about their safety, biocompatibility, and toxicity.…”

Encapsulation of gallic acid/cyclodextrin inclusion complex in electrospun polylactic acid nanofibers: Release behavior and antioxidant activity of gallic acid

“…Various polymeric nanofibers have been already produced by using electrospinning technique. In addition to that, flexibility of this process enables to obtain nanofibers containing active agents which have potential to be used in diverse application areas [13][14]. Therefore, gallic acid encapsulated polymeric films and electrospun nanofibers have been studied previously [3,5,[15][16].…”