Using aortic distensibility index to detect coronary stenosis

Shehata, Mohamed; Elsayegh, Ayah Tarek; Gomaa, Yasser A.; Gamal, Mohamed

doi:10.1080/ac.70.4.3096895

Cited by 3 publications

(5 citation statements)

References 25 publications

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“…ADI in the present study was found to decrease with increased severity of stenosis (P< 0.0011). In concordance with our study, in [24] study, patients with significant obstructive CAD showed significantly lower ADI values.…”

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosissupporting

confidence: 92%

“…ADI in the present study was inversely correlated with the degree of stenosis (r=-0.707, P< .001). In agreement with our finding, [24] found a significant inverse correlation between aortic distensibility measured using computed tomographic angiography and severity of coronary artery disease (percent luminal stenosis) r = -0.244, P = 0.045).…”

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosissupporting

confidence: 92%

“…In the current study, there was a significant negative correlation between calcium scoring and the ADI (r= -0.771, P< .001). Similarly, [24] found a significant inverse correlation between aortic distensibility measured using computed tomographic angiography and CAC scoring (r = -0.265, P= 0.042).…”

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosismentioning

confidence: 74%

“…They also found AD to be a good predictor of CV events similar to ejection fraction and may therefore be an early sign of CAD". Moreover, [24] found "a negative correlation between number of diseased coronary arteries and ADI. Yet, the correlation was not significant (r = -0.067, P = 0.578)".…”

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosismentioning

confidence: 99%

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Correlation between Impaired Aortic Distensibility and the Severity of Coronary Artery Disease and Calcium Scoring Measured by Cardiac CT

Alshameery

El-Yazal

Mansy

2022

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Background: Multi-Slice cardiac CT has evolved as a noninvasive imaging technique for evaluation of stenosis in the coronary arteries by what is called Coronary Computed Tomographic Angiography (CCTA), but it is also widely used in quantitative plaque assessments through Coronary Artery Calcium (CAC) scoring and plaque type identification ( soft or Mixed VS calcific) . Evaluation of aortic distensibility and aortic stiffness can also be performed through Multi-Slice Computed Tomography (MSCT) by calculating Aortic Distensibility Index (ADI) and Pulse Wave Velocity (PWV). Aim: To evaluate whether impaired Aortic Distensibility Index (ADI) and Aortic Stiffness measured by Cardiac CT is correlating with the severity of coronary artery disease and coronary calcium scoring in at-risk individuals (assessed by CCTA). Patients and Methods: We included 180 patients. Patients were classified into four groups according to their CAC score and according to the degree of stenosis based on CCTA. All patients in this study have underwent full history taking, short clinical examination including B.P. and H.R. measurements, standard ECG, routine laboratory investigations, and Multi-Slice CT Coronary Angiography (MSCT-CA). All patients underwent coronary artery calcium (CAC) scanning and CCTA, and their ADI and Aortic Stiffness were measured. Maximum systolic and maximum diastolic cross sectional-area (CSA) of ascending-aorta (AAo) was measured 15-mm above the left main coronary ostium. ADI was defined as: [(Systolic CSA –Diastolic CSA)/ (Diastolic CSA in X systemic-pulse-pressure) X 103]. Aortic stiffness was measured as PWV using Bramwell-Hill equation [1] [(3.57/ √distensibility)]. Results: There were strong correlation between Aortic distensibility and Aortic stiffness (PWV) with degree of stenosis and coronary artery calcium. In patients stratified based on the degree of calcium scoring (CAC score), there was a statistically significant negative correlation between calcium scoring and the ADI (Pearson's r= -0.771, p< .001), and a statistically significant positive correlation between calcium scoring and PWV (Pearson's r=0.817, p< .001). In patients stratified based on the degree of stenosis, there was a statistically significant negative correlation between ADI and the Degree of stenosis (Pearson's r=-0.707, p< .001), and there was a statistically significant positive correlation between PWV and the Degree of stenosis (Pearson's r=0.697, p< .001). Conclusion: Impaired aortic distensibility strongly correlates with the severity of coronary atherosclerosis, degree of stenosis and coronary artery calcium. Addition of ADI to CAC and traditional risk factors provides incremental value to predict at-risk individuals.

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Section: Fig 8 the Correlation Between Adi And Degree Of Stenosissupporting

confidence: 92%

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosissupporting

confidence: 92%

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosismentioning

confidence: 74%

Section: Fig 8 the Correlation Between Adi And Degree Of Stenosismentioning

confidence: 99%

See 2 more Smart Citations

Correlation between Impaired Aortic Distensibility and the Severity of Coronary Artery Disease and Calcium Scoring Measured by Cardiac CT

Alshameery

El-Yazal

Mansy

2022

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“…Several noninvasive diagnostic methods have been used to measure Ao elasticity in human medicine. [11][12][13][14][15][16][17][18][19][20][21] In small animal practice, noninvasive measurement of Ao elastic properties could help clinicians differentiate between secondary or idiopathic SH and situational SH, as well as to overcome measurement difficulties caused by animal movements and tremors.…”

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confidence: 99%

Ultrasonographic assessment of abdominal aortic elasticity in hypertensive dogs

Corda

Caivano

et al. 2020

Veterinary Internal Medicne

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Background: Systemic hypertension (SH) is a persistent and pathological increase in arterial blood pressure (BP). Chronic SH leads to an increase in aortic (Ao) stiffness, and measuring Ao elasticity is useful for estimating Ao stiffness in humans. Currently, no literature in veterinary medicine describes noninvasive assessment of abdominal Ao elasticity in dogs with SH. Objective: Compare ultrasonographic-derived abdominal Ao strain (AoSt) between hypertensive (HT) and normotensive (NT) dogs. Animals: Fifty privately-owned dogs with clinical signs, conditions, or both potentially associated with SH. Methods: Prospective observational case-control study. Aortic stiffness was estimated by calculating AoSt as follows: AoSt = ([AoDs − AoDd]/AoDd) × 100, where AoDs and AoDd are the Ao diameter in systole and in diastole, respectively. Aortic stiffness was calculated from 2 different Ao transverse sections, the first caudal to the left renal artery (K_AoSt), and the second cranial to the external iliac arteries (I_AoSt). Results: Thirty-two dogs were included in the HT group and 18 in the NT group. Both K_AoSt and I_AoSt in HT dogs were significantly lower (P < .05) than in NT dogs (7.4 ± SD 3.6) vs 10.3 (±3.8) and 5.7 (interquartile range [IQR], 3.9-7.5) vs 8.1 (IQR, 7-10.3), respectively. Only K_AoSt was significantly influenced by age. Conclusions and Clinical Importance: Ultrasonographic Ao elasticity assessment was feasible to compare HT and NT dogs. Results indicated that K_AoSt and I_AoSt indices can be used to assess SH-related Ao stiffness, especially when indirect BP

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