Eye movement-based analyses have been extensively performed on graphical user interface designs, mainly on high-fidelity prototypes such as coded prototypes. However, practitioners usually initiate the development life cycle with low-fidelity prototypes, such as mock-ups or sketches. Since little or no eye movement analysis has been performed on the latter, would eye tracking transpose its benefits from high-to low-fidelity prototypes and produce different results? To bridge this gap, we performed an eye movement-based analysis that compares gaze point indexes, gaze event types and durations, fixation and saccade indexes produced by N =8 participants between two treatments, a paper prototype vs. a wireframe. The paper also reports a qualitative analysis based on the answers provided by these participants in a semi-directed interview and on a perceived usability questionnaire with 14 items. Due to its interactivity, the wireframe seems to foster a more exploratory approach to design (e.g., testing and navigating more extensively) than the paper prototype.