2015
DOI: 10.1097/dbp.0000000000000194
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Using the M-CHAT-R/F to Identify Developmental Concerns in a High-Risk 18-Month-Old Sibling Sample

Abstract: Objective Given the high autism spectrum disorder (ASD) recurrence risk in younger siblings, it is important to identify early ASD markers within this high risk population. Although there is increasing evidence that the Modified Checklist for Autism in Toddlers-Revised, with Follow-Up Interview can identify many low-risk children during the second year of life, there has yet to be a study of how the M-CHAT-R/F functions in a high-risk sibling population at very young ages. Methods As part of a larger populat… Show more

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Cited by 23 publications
(15 citation statements)
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References 29 publications
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“…One would expect such a high positive risk rate when screening a sample of children for whom there is already concern in the social-communication domain [ 2 , 9 ]. Children in our study with versus without a family history of ASD had a much higher likelihood of presenting risk on ASD-specific screening and social-communication developmental screening, consistent with previous research [ 35 , 36 ]. It is not surprising that in a sample of parents concerned about their child’s social-communication development, there is a high rate of family history of ASD, which justifiably raises parents’ concerns given the high recurrence rates of ASD [ 6 ] and parents’ awareness of ASD symptom manifestation [ 9 ].…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…One would expect such a high positive risk rate when screening a sample of children for whom there is already concern in the social-communication domain [ 2 , 9 ]. Children in our study with versus without a family history of ASD had a much higher likelihood of presenting risk on ASD-specific screening and social-communication developmental screening, consistent with previous research [ 35 , 36 ]. It is not surprising that in a sample of parents concerned about their child’s social-communication development, there is a high rate of family history of ASD, which justifiably raises parents’ concerns given the high recurrence rates of ASD [ 6 ] and parents’ awareness of ASD symptom manifestation [ 9 ].…”
Section: Discussionsupporting
confidence: 91%
“…However, this approach identified 2 children who would have been missed if the M-CHAT-R/F had been administered only to those who screened positive on the initial M-CHAT-R questionnaire. The interspersed procedure may have led to elevated risk rates on the M-CHAT-R as our risk rates were higher than those reported in another study of infant siblings of children with ASD [ 36 ]. At the same time in addition to the family history of ASD, parents in our study had specific social-communication concerns suggesting that elevated risk rates were not solely associated with measurement.…”
Section: Discussioncontrasting
confidence: 61%
“…There is growing evidence that ASD can often be diagnosed during the second year of life, usually at 12-15 months,[4] before the child's third birthday. [120] Early detection of developmental disorder is essential for early intervention, because early comprehensive behavioral interventions can improve social communication,[2] and provide the better chance for better outcome. [2122] The American Academy of Pediatrics recommends ASD-specific screening of all children between 18 and 24 months of age because there are critical times for early social and language development.…”
Section: Introductionmentioning
confidence: 99%
“…73 Some of the cognitive, neuromotor, and behavioral sequelae may not be apparent for months or years after the injury, when a child is expected to perform higher-level cognitive activities. 81,82 Parents report particular difficulty in managing the behavior of children who suffered frontal lobe injuries caused by AHT. 72 Autism spectrum disorder has been described in children who have suffered AHT.…”
Section: Ahtmentioning
confidence: 99%