Using the Region of Interest from Time-of-Flight Magnetic Resonance Angiography to Differentiate Between Intracranial Arterial Dissection and True Atherosclerotic Stenosis

Hwang, Jung Won; Jung, Jun‐Sub; Hyung, Jae; Jung, Il Nam; Park, Moon Ho; Kwon, Do Young; Kim, Jiyeon; Kim, Yool Hee; Lee, Sang Hun

doi:10.1159/000496505

Cited by 4 publications

(1 citation statement)

References 18 publications

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“…The scanning sequence included three-dimensional time-of-flight magnetic resonance angiography (3D-TOF MRA) and three dismensional-T1 weighted sampling perfection with application of optimized contrasts using different flip angle evolution (3D-T1WI SPACE). The parameters for 3D-TOF MRA and 3D-T1WI SPACE have been described elsewhere [17,18]. After the 3D-TOF MRA and 3D-T1WI SPACE scanning sequences, the patient's cubital vein was connected to a high-pressure syringe and 20 mL of gadoterate meglumine and 30 mL of normal saline were injected.…”

Section: Hr-mri Acquisitionmentioning

confidence: 99%

Assessment of Morphological Features and Imaging Characteristics of Patients with Intracranial Artery Dissection: A High-Resolution MRI Study

Wu¹,

Liu²,

Duan³

et al. 2022

J. Integr. Neurosci.

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Background: Intracranial artery dissection (IAD) is a pathological dissection of the arterial wall. .However, the morphological features and imaging characteristics of patients with intracranial artery dissection (IAD) remain poorly understood. Methods: The study reports on 70 IAD patients (30 culprit and 40 non-culprit). All participants underwent high-resolution magnetic resonance imaging (HR-MRI) scans. The morphological features and imaging characteristics of artery dissection were carefully investigated. Demographics and clinical characteristics of culprit and non-culprit patients were also collected. Apparent differences between the two groups, which could be used as biomarkers for ischemic event caused by the culprit dissection, were identified by receiver operating characteristic (ROC) curve analysis. Results: The IAD patients studied could be classified into five different types on the basis of morphological features: classical dissection (n = 31), fusiform aneurysm (n = 2), long dissected aneurysm (n = 9), dolichoectatic dissecting aneurysm (n = 6), and saccular aneurysm (n = 22). The direct sites of artery dissection (double lumen and intimal flap) can be seen in most IAD patients on HR-MRI. Additionally, the presence of hypertension, double lumen and intimal flap were associated with culprit lesions and might be considered biomarkers for the ischemic event caused by the culprit dissection. Conclusions: Analysis showed that HR-MRI allowed easy visualization of abnormal morphology of artery dissection lesions. This was of great significance for the diagnosis of IAD and gave a better understanding of its pathophysiological mechanism.

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Section: Hr-mri Acquisitionmentioning

confidence: 99%

Assessment of Morphological Features and Imaging Characteristics of Patients with Intracranial Artery Dissection: A High-Resolution MRI Study

Wu¹,

Liu²,

Duan³

et al. 2022

J. Integr. Neurosci.

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High-resolution magnetic resonance imaging for the follow-up of intracranial arterial dissections

2020

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Comparison of 3D T1-SPACE and DSA in evaluation of intracranial in-stent restenosis

Shao

et al. 2020

The British Journal of Radiology

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Objective: In-stent restenosis (ISR) after stenting for intracranial stenosis is a significant issue. This study aimed to evaluate the usefulness of the 3D T1-SPACE technique in the follow-up of patients after stent implantation. Methods: Fifteen patients with intracranial arterial stenosis were prospectively enrolled 6–8 months after stenting. Digital subtraction angiography (DSA) and 3D T1-SPACE imaging were performed to evaluate the degree of stenosis and the enhancement of the vessel wall. Bland–Altman plots were used to assess the agreement between the two imaging methods, and the Pearson correlation coefficient was calculated as a measure of the linear correlation. Results: Eight Enterprise stents and seven Wingspan stents were used in 15 patients. The follow-up DSA after 6–8 months showed that the degree of stenosis was 40% (range, 30–72%), and ISR occurred in 4 of 15 (26.7%) lesions. The degree of stenosis assessed using the 3D T1-SPACE imaging technique was 35% (range, 30–75%). All four patients with ISR demonstrated significant enhancement. The Pearson correlation coefficient between the two methods was 0.959 (p < 0.05), and the Bland–Altman plot showed that all data points were within the consistency limits ([Formula: see text] ± 1.96 s). Conclusion: As a non-invasive imaging modality, 3D T1-SPACE showed great consistency with DSA in measuring the degree of stenosis after intracranial stenting. It may be used as an optional method for detecting ISR. Advances in knowledge: This study evaluated the usefulness of 3D T1-SPACE technique in the follow-up of patients after stent implantation, which could be used as an optional and non-invasive method in detection of in-stent restenosis.

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Using the Region of Interest from Time-of-Flight Magnetic Resonance Angiography to Differentiate Between Intracranial Arterial Dissection and True Atherosclerotic Stenosis

Cited by 4 publications

References 18 publications

Assessment of Morphological Features and Imaging Characteristics of Patients with Intracranial Artery Dissection: A High-Resolution MRI Study

Assessment of Morphological Features and Imaging Characteristics of Patients with Intracranial Artery Dissection: A High-Resolution MRI Study

High-resolution magnetic resonance imaging for the follow-up of intracranial arterial dissections

Comparison of 3D T1-SPACE and DSA in evaluation of intracranial in-stent restenosis

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