Uterine dehiscence in term pregnant patients with one previous cesarean delivery: Growth factor immunoexpression and collagen content in the scarred lower uterine segment

Pollio, Fabrizio; Staibano, Stefania; Mascolo, Massimo; Salvatore, G; Persico, Francesco; Falco, Massimo De; Lieto, Andrea Di

doi:10.1016/j.ajog.2005.07.048

Cited by 51 publications

(42 citation statements)

References 25 publications

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“…Our data suggest, that emergency CS is also a risk factor for abnormal healing of the CS scar. This finding is in accordance with previous studies [23][24][25].…”

Section: Discussionsupporting

confidence: 83%

Ultrasonography of the uterus within 6 weeks following Cesarean section

2012

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“…Our data suggest, that emergency CS is also a risk factor for abnormal healing of the CS scar. This finding is in accordance with previous studies [23][24][25].…”

Section: Discussionsupporting

confidence: 83%

Ultrasonography of the uterus within 6 weeks following Cesarean section

2012

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“…All of these factors control the production of collagen in the healing area. 7,8 Pollio et al 9 reported higher collagen content in the areas of CSD compared with the well-healed cesarean scars. This finding was attributed to lower-than-normal transforming growth factor–β3 and connective tissue growth factor.…”

Section: Discussionmentioning

confidence: 98%

Robotic Repair of Uterine Dehiscence

Rosa¹,

McCarthy

Richter

et al. 2013

JSLS

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“…The incidence of massive intraoperative bleeding has reached 32%-73% [5, 6, 12]. Because only a few rigid and brittle muscle fibers exist within the scar [1, 21–24], it could be very difficult to cease the massive bleeding by traditional medical measures without UAE, even under hysteroscopy [19, 25–28]. Deans et al have reported the use of hysteroscopy to treat six CSP patients without blocking the blood supply.…”

Section: Discussionmentioning

confidence: 99%

Combined laparoscopy and hysteroscopy vs. uterine curettage in the uterine artery embolization-based management of cesarean scar pregnancy: a retrospective cohort study

Zhu

et al. 2014

BMC Women's Health

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BackgroundThe number of cesarean scar pregnancy (CSP) has significantly increased in the recent decade. Although uterine artery embolization (UAE) has been adopted to minimize the blood loss during uterine curettage removing of CSP, massive bleeding and uterine rupture can still be frequently encountered. The aim of this study was to compare the efficacy and safety of a novel combined laparoscopy and hysteroscopy technique with the traditional curettage in removing the conceptus and repairing the incision defect following the UAE management of CSP.MethodsThe CSP patients (n = 58) diagnosed between March 1, 2005 and March 1, 2010 were enrolled in three medical centers in Shanghai, China. All of these patients have undergone intra-arterial methotrexate, UAE and one of the following treatments: combined laparoscopy and hysteroscopy (study group, n = 25) and uterine curettage (control group, n = 33). Their medical records and 2-year outcomes were reviewed. The CSP removal rate, amount of blood loss during the treatment, incision repair rate (note: the post-curettage healing process of the incision defect was seen as a form of natural incision repairing, i.e., the self-repair mode), hospital stay, β-hCG regression time and postoperative sequelae were compared between two groups.ResultsThe CSP removal rate in the study group (100%) was significantly higher than that (79%) in the control group (p = 0.024). The average blood loss was 78.0 mL in the study group, which was much less than the 258.5 mL (p = 0.004) in the control group. A satisfactory incision repair rate (96%) was achieved in the study group, while it was 25% (p < 0.001) in the control group. Moreover, the study group had significantly shorter hospital stays (p = 0.043) and β-hCG regression times (p = 0.033), lower rates of postoperative abdominal pain (p = 0.035) and menstruation abnormalities (p = 0.043).ConclusionsCombined laparoscopy and hysteroscopy is much safer and more effective than uterine curettage as a supplementary measure to remove the conceptus and repair the cesarean incision following the UAE management of CSP.

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Uterine dehiscence in term pregnant patients with one previous cesarean delivery: Growth factor immunoexpression and collagen content in the scarred lower uterine segment

Cited by 51 publications

References 25 publications

Ultrasonography of the uterus within 6 weeks following Cesarean section

Ultrasonography of the uterus within 6 weeks following Cesarean section

Robotic Repair of Uterine Dehiscence

Combined laparoscopy and hysteroscopy vs. uterine curettage in the uterine artery embolization-based management of cesarean scar pregnancy: a retrospective cohort study

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