Uterine T cell lymphoma in a mare, with multicentric involvement

Freeman, Sarah; Bjornson, S.; Smith, Richard

doi:10.1136/vr.141.15.391

Cited by 8 publications

(7 citation statements)

References 18 publications

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“…Multicentric lymphoma, the most common form of equine lymphoma, is characterised by widespread involvement of lymph nodes, peripheral and/or internal, and a variety of organs most likely through distribution of neoplastic lymphocytes via lymphatic circulation (Neufeld 1973;van den Hoven and Franken 1983;Savage 1998;McClure 2000;Knottenbelt 2003;Schneider 2003;Meyer et al 2006;Munoz et al 2009). Liver, spleen, intestine, kidney and bone marrow (leukaemic lymphoma) are the organs most commonly affected, but lymphoma of the upper airway, central nervous system, heart, adrenal glands, reproductive organs and eye have also been reported (Madewell et al 1982;Allen et al 1984;Browning 1986;Staempfli et al 1988;Murphy et al 1989;Held et al 1992;Freeman et al 1997;Labelle and De Cock 2005;Stoppini et al 2005;Germann et al 2008;Morrison et al 2008). Clinical signs of multicentric lymphoma reflect the function of organs involved, thus a multitude of symptoms may be present at one time, but horses with the multicentric form of lymphoma commonly have weight loss, oedema of the ventral body wall, elevated temperature, pulse and respiration, and enlarged lymph nodes (lymphadenopathy) (Neufeld 1973;van den Hoven and Franken 1983;Savage 1998;McClure 2000;Knottenbelt 2003;Schneider 2003;Meyer et al 2006;Munoz et al 2009).…”

Section: Multicentric Lymphomamentioning

confidence: 99%

Equine lymphoma

Taintor¹,

Schleis

2011

Equine Veterinary Education

113

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Section: Multicentric Lymphomamentioning

confidence: 99%

Equine lymphoma

Taintor¹,

Schleis

2011

Equine Veterinary Education

113

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“…Furthermore it also helps to guide sampling of the mass when no neoplastic cells were found in pleural fluid cytology . Imaging findings have also been described in clinical cases with lymphoma involving the head and other anatomical locations …”

Section: Introductionmentioning

confidence: 96%

Ultrasonographic Findings in 13 Horses With Lymphoma

Janvier

Evrard

Cerri

et al. 2015

Vet Radiology Ultrasound

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Ultrasonography and radiography are commonly used for staging of lymphoma in horses, however there is little published information on imaging characteristics for horses with confirmed disease. The purpose of this retrospective, case series study was to describe ultrasonographic and radiographic findings for a group of horses with a confirmed diagnosis of lymphoma. A total of 13 horses were sampled. Lymphadenopathy (8/13), peritoneal effusion (6/13), splenic (6/13), and hepatic (5/13) lesions were the most frequently identified. The predominant splenic and hepatic ultrasonographic lesions were hypoechoic nodules, organomegaly, and changes in echogenicity. Digestive tract lesions were detected in three horses and these included focal thickening and decreased echogenicity of the small (2/13) and large intestinal (2/13) wall. Thoracic lesions were predominantly pleural effusion (4/13), lymphadenopathy (4/13), and lung parenchymal changes (3/13). Enlarged lymph nodes were detected radiographically (4/13) and/or ultrasonographically (2/13) in the thorax and ultrasonographically in the abdomen (7/13) and in the caudal cervical region (4/13). Findings supported the use of abdominal and thoracic ultrasonography for lymphoma staging in horses. Ultrasound landmarks for localizing cecal and caudal deep cervical lymph nodes were also provided.

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“…To the authors' knowledge, uterine B cell lymphoma in the mare has not previously been reported in the literature. A few other reports showed involvement of the uterus although these reported cases were either T cell lymphoma (Freeman et al . 1997) or were cases in which the cell lineage was not well defined or reported (Neufeld 1973; Sweeney et al .…”

Section: Discussionmentioning

confidence: 99%

“…1980), lymphosarcoma (Neufeld 1973), adenocarcinoma (Gunson et al . 1980) and T cell lymphoma (Freeman et al . 1997) have been previously described in the mare.…”

Section: Introductionmentioning

confidence: 99%

Uterine B cell lymphoma in a mare

Claes¹,

Ball²,

Liu³

et al. 2012

Equine Veterinary Education

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SummaryIn this report, we describe the diagnostic findings and outcome of a uterine B cell lymphoma in a mare. A well circumscribed uterine mass with significant peripheral vascularisation was identified by transrectal ultrasonography during the reproductive examination of an 8-year-old Thoroughbred mare. Subsequent hysteroscopy revealed that the uterine mass was located intramurally and contained a protruding polyp-like structure. A diagnosis of uterine B cell lymphoma was established by histopathological examination of a hysteroscopically-obtained tissue sample. Additional diagnostics demonstrated that the uterus was a site of metastasis. Due to her deteriorating condition, extensiveness of the tumour and poor prognosis, the owner decided that the mare should be subjected to euthanasia.

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Uterine T cell lymphoma in a mare, with multicentric involvement

Cited by 8 publications

References 18 publications

Equine lymphoma

Equine lymphoma

Ultrasonographic Findings in 13 Horses With Lymphoma

Uterine B cell lymphoma in a mare

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