Utilising alternative modifications of α-olefin end groups to synthesise amphiphilic block copolymers

Abstract

Amphiphilic block copolymers comprised of polyisobutylene (PIB) and poly(2-(dimethylamino)ethyl methacrylate) (DMAEMA) have been synthesised.

Acetylene Dicarboxylic Acid Diallyl Ester: A Versatile Monomer for Thiol–Ene Photocured Networks

“…2-Azidoethanol [46] (2.48 g, 28.4 mmol) was dissolved in 50 mL of CH 2 Cl 2 in a round bottom flask, then Et 3 N (3.94 mL, 28.4 mmol) was added to the reaction mixture, and placed on an ice bath while stirring. Phenyl dichlorophospate (1.416 mL, 9.5 mmol) was added to the reaction medium dropwise and the reaction mixture was stirred at 0 °C for 30 min and overnight at room temperature.…”

Recent Developments in the Synthesis of Biomacromolecules and their Conjugates by Single Electron Transfer–Living Radical Polymerization

“…SET-LRP of ethyl methacrylate (EMA), butyl methacrylate ( n -BMA), ,, tert -butyl methacrylate ( t -BMA), methyl adamantly methacrylate (MAMA), and isobornyl methacrylate (IBMA) also produced the corresponding polymethacrylates, whereas methacrylic acid (MAA) could be copolymerized with MMA . Hydrophilic methacrylates such as 2-hydroxyethyl methacrylate (HEMA), di­(ethylene glycol) methyl ether methacrylate (DEGMEMA), tri­(ethylene glycol) methyl ether methacrylate (TEGMEMA), oligo­(ethylene glycol) methyl ether methacrylate (OEGMEMA), − and the corresponding azide (OEGMA-N 3 ) and hydroxyl (OEGMA–OH) derivatives, functional methacrylates such as 2-( tert -butyl-aminoethyl) methacrylate (t-BAMA), 2-(dimethylamino) ethyl methacrylate (DMAEMA), 2-(diethylamino)­ethyl methacrylate (DEAEMA), and γ-butyrolactone methacrylate (GBLMA), as well as ionic N , N -compounds such as dimethyl- N -methacryloyloxyethyl- N -sulfobutyl ammonium (DMSA) and [2-(methacryloxy)­ethyl]­trimethylammonium chloride (MAETC) have also been successfully polymerized under optimized SET-LRP conditions. Complex methacrylates such as 1′-(2-methacryloxyethyl)-3′,3′-dimethyl-6-nitrospiro­(2 H -1-benzopyran-2,2′-indoline) (SPMA) and 7-(2-methacryloyloxy)-4-methylcoumarin (CMA) also tolerated the mild reaction conditions of SET-LRP.…”

“…Since the pioneer work of Monteiro and co-workers, SET-LRP has been proven to be an outstanding tool for the precise preparation of a variety of amphiphilic block copolymers with different architectures with, in some cases, promising applications. ,,,,,,,− Taking advantage of SET-LRP, Monteiro and co-workers reported the preparation of linear and 4-armed star copolymers composed of MA and SA . The subsequent deprotection of the solketal side chains produced amphiphilic copolymers that self-assembled in water into micellar and vesicular structures.…”