2016
DOI: 10.4103/2141-9248.183936
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Utility of bacillary index in slit skin smears in correlation with clinical and histopathological alterations in hansen's disease: An attempt to revive a simple useful procedure

Abstract: Leprosy, a relatively common chronic contagious disease having diverse modes of clinical presentation, can mimic a variety of unrelated diseases. For proper and adequate treatment, the diagnosis must be made accurately with subtyping which should be done with the help of bacillary index, histopathological features, and clinical correlation. This is extremely important in patient care as paucibacillary and multibacillary types have different modes of treatment. Our aim is to categorize leprosy into various type… Show more

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Cited by 9 publications
(5 citation statements)
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“…However, presence of M. leprae DNA at the examined sites had been identified through tests of higher sensitivity (qPCR and anti-PGL-I IgM ELISA), and high bacillary loads were observed through serological tests (Azevedo et al, 2017;Cho et al, 1991). Positive bacillary indices correlated more accurately with the LL form, which is associated with the presence of greater quantities of bacilli in the skin (Premalatha et al, 2016).…”
Section: Discussionmentioning
confidence: 87%
“…However, presence of M. leprae DNA at the examined sites had been identified through tests of higher sensitivity (qPCR and anti-PGL-I IgM ELISA), and high bacillary loads were observed through serological tests (Azevedo et al, 2017;Cho et al, 1991). Positive bacillary indices correlated more accurately with the LL form, which is associated with the presence of greater quantities of bacilli in the skin (Premalatha et al, 2016).…”
Section: Discussionmentioning
confidence: 87%
“…Similar findings were seen in the study conducted by Semwal et al, 7 Karki et al 8 and Ramos et al 9 Male predominance is thought to be because of factors such as industrialization and urbanization which increases incidence for contact in males. 10 In our study, the majority of patients belonged to the age group of 21 to 30 years (33.9%) followed by 31 to 40 years (16.1%) (Table1). This is similar to findings reported by Mathan R et al 16 with common age group of 21 to 40 years.…”
Section: Discussionmentioning
confidence: 51%
“…It is found that the BI is maximum in LL and BL where as IL, BT and TT had low BI (Table 4). The study conducted by Premalatha et al 10 and Semwal et al 7 also showed similar features of multibacillary in BL, LL and paucibacillary in TT and BT. The FF stained sections of BL and LL showed globi of bacilli within leprae cells with BI five to six (Fig.4) whereas IL, BT and TT had BI of upto three.…”
Section: Discussionmentioning
confidence: 60%
“…29 This is consistent with the study done by Premalatha et al which described a true correlation between AFS and histopathology. 30…”
Section: Discussionmentioning
confidence: 99%