Utility of daily image guidance with intensity‐modulated radiotherapy for tumors of the base of skull

Chen, Allen M.; Cheng, Suzan; Farwell, D. Gregory; Luu, Quang; Donald, Paul J.; Boggan, James E.; Franklin, Stephen; Purdy, James A.

doi:10.1002/hed.21805

Cited by 10 publications

(6 citation statements)

References 47 publications

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“…The general consensus is that an individual approach is best suited for HN patients in deciding to adapt radiotherapy. With this in mind, HN patients should be monitored with CT or CBCT imaging acquired during frequent (daily or weekly) intervals throughout treatment . These images are reviewed by a radiation oncologist who then decides whether the treatment plan is to be adapted.…”

Section: Introductionmentioning

confidence: 99%

A novel surrogate to identify anatomical changes during radiotherapy of head and neck cancer patients

Gros

Roeske

et al. 2017

Medical Physics

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This novel method provides an efficient tool to visualize 3D external anatomical changes on a single 2D map. It quickly pinpoints the location of differences in anatomy during the course of radiotherapy, which can help physicians determine if a treatment plan needs to be adapted. The interactive graphic user interface developed in this study will be evaluated in an adaptive radiotherapy workflow for head and neck patients in a future prospective trial.

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Section: Introductionmentioning

confidence: 99%

A novel surrogate to identify anatomical changes during radiotherapy of head and neck cancer patients

Gros

Roeske

et al. 2017

Medical Physics

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“…Dose conformality to the target volume and conformal avoidance of the organs at risk achieved through IMRT may provide better local control and less optic toxicity compared to conventional radiotherapy technique. Image-guided radiation therapy (IGRT) has also been introduced to complement these approaches in ensuring the safe delivery of a highly conformal treatment, by facilitating convenient and frequent imaging of the patient anatomy throughout the treatment course [54].…”

Section: Results Of Treatmentmentioning

confidence: 99%

Sinonasal Cancers: Diagnosis and Management

Sharma¹,

Sharma²,

Sharma³

2019

Challenging Issues on Paranasal Sinuses

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Sinonasal cancers are rare tumors constitute 3% of head and neck cancers. These include malignancies of the nasal cavity and paranasal sinuses (maxillary sinus, ethmoid sinuses, frontal sinus and sphenoid sinus). Patients are often asymptomatic until late in the course of their disease. Tumors of the maxillary sinus are more common than those of the ethmoid sinus or nasal cavity. The workup for patients with suspected paranasal sinus tumors includes complete head and neck CT/MRI with contrast. FDG-PET/CT may be considered in the workup of patients with clinically apparent stage III or IV disease. The most common histology for these tumors is squamous cell carcinoma, others reported includes adenocarcinoma, esthesioneuroblastoma, minor salivary gland tumors, or sinonasal neuroendocrine carcinoma [SNEC]). Surgical resection for all T stages (except T4b, any N) followed by postoperative therapy remains a cornerstone of treatment. However, definitive RT or systemic therapy/RT is recommended for T4b, any N. Locoregional control and incidence of distant metastasis are dependent on T stage, N stage, and tumor histology.

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“…Overall, we have introduced a new RF localization system that overcomes the main weaknesses of existing intrafraction motion tracking systems [ 5 , 19 , 20 ]. This system is robust against changes in patient anatomy and provides real-time tracking of changes in complex patient positioning, without requiring line-of-sight detection and avoiding extra dose to a patient.…”

Section: Discussion and Conlusionsmentioning

confidence: 99%

A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy

Ostyn

Kim

Yeo

2016

Sensors

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One of the most widely used tools in cancer treatment is external beam radiotherapy. However, the major risk involved in radiotherapy is excess radiation dose to healthy tissue, exacerbated by patient motion. Here, we present a simulation study of a potential radiofrequency (RF) localization system designed to track intrafraction motion (target motion during the radiation treatment). This system includes skin-wearable RF beacons and an external tracking system. We develop an analytical model for direction of arrival measurement with radio frequencies (GHz range) for use in a localization estimate. We use a Monte Carlo simulation to investigate the relationship between a localization estimate and angular resolution of sensors (signal receivers) in a simulated room. The results indicate that the external sensor needs an angular resolution of about 0.03 degrees to achieve millimeter-level localization accuracy in a treatment room. This fundamental study of a novel RF localization system offers the groundwork to design a radiotherapy-compatible patient positioning system for active motion compensation.

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Utility of daily image guidance with intensity‐modulated radiotherapy for tumors of the base of skull

Abstract: The feasibility and efficacy of daily IGRT as a complement to IMRT for skull base were demonstrated.

Cited by 10 publications

References 47 publications

A novel surrogate to identify anatomical changes during radiotherapy of head and neck cancer patients

A novel surrogate to identify anatomical changes during radiotherapy of head and neck cancer patients

Sinonasal Cancers: Diagnosis and Management

A Simulation Study of a Radiofrequency Localization System for Tracking Patient Motion in Radiotherapy

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