Utility of indirect sonographic signs (including cavum septum pellucidum ratio) in midgestational screening for partial agenesis of corpus callosum

Zhao, Di; Wang, Bing; Cai, Ailong

doi:10.1002/jcu.22722

Cited by 5 publications

(5 citation statements)

References 22 publications

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“…An initial qualitative analysis of 27 studies was performed. After this initial analysis, three studies published prior to 1990 were excluded, yielding a total of 24 studies included in the final analysis 12–35 . Table S2 shows a summary of the studies using the PICOS framework as a guide.…”

Section: Resultsmentioning

confidence: 99%

“…In the early 1990s, dedicated fetal neurosonography was added to the diagnostic work-up, and fetal MRI 12 Bennett (1996) 13 d'Ercole (1998) 14 Glenn (2005) 15 Volpe (2006) 16 Manfredi (2010) 17 Lerman-Sagie (2009) 18 Cignini (2010) 19 Ghi (2010) 20 Paladini (2013) 21 Pashaj (2015) 22 Craven (2015) 23 Alby (2016) 24 R üland (2015) 25 Shen (2015) 26 Shinar (2016) 27 Manganaro (2017) 28 Karl (2017) 29 Manevich-Mazor (2018) 30 Zhao (2019) 31 Turkyilmaz (2019) 32 Santirocco (2021) 33 Meidan (2019) 34 Jarre (2017) 35 Only first author of each study is given. A maximum of four stars could be given for selection, two for comparability and three for outcome.…”

Section: Imaging Modalitiesmentioning

confidence: 99%

“…Since that first report, advances in fetal imaging, using both ultrasound and, more recently, magnetic resonance imaging (MRI), have led to increased recognition of fetal CC pathologies. CC anomalies are categorized broadly 7–9 into either complete (CACC) or partial (PACC) agenesis of the CC, but the prenatal imaging literature also includes a variety of descriptive terms, such as short, thick or thin CC, for these pathologies 10–35 . Developmental anomalies of the CC can be isolated or associated with other central nervous system (CNS) or non‐CNS malformations, and known etiological factors range from genetic factors and teratogens to infections and ischemia 9,36–40 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Heterogeneity in defining fetal corpus callosal pathology: systematic review

Mahallati

Sotiriadis

Celestin

et al. 2021

Ultrasound in Obstet & Gyne

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Objective Fetal anomalies of the corpus callosum (CC) have been reported in the prenatal imaging literature since 1985, and, especially when isolated, pose challenges for both the patient and fetal medicine specialist. The purpose of this study was to review systematically the literature on prenatally diagnosed abnormalities of the CC, focusing on the terminology used to describe abnormalities other than complete agenesis of the CC, and to assess the heterogeneity of the nomenclature and definitions used. Methods This study was conducted in accordance with the PRISMA statement for reporting systematic reviews. A literature search was performed to identify prospective or retrospective case series or cohort studies, published in English, French, Italian, German or Spanish, reporting fetal imaging findings and describing anomalies of the CC. Quality and risk of bias of the studies were evaluated using the Newcastle–Ottawa scale and a modification of the scale developed by Conde‐Agudelo et al. for other fetal imaging studies. The data extracted included the number of patients, the number of different anomalies identified, the descriptive names of the anomalies, and, where applicable, the definitions of the anomalies, the number of cases of each type of anomaly and the biometric charts used. Secondary tests used to confirm the diagnosis, as well as the postnatal or post‐termination tests used to ascertain the diagnosis, were also recorded. Results The search identified 998 records, and, after review of titles and abstracts and full review of 45 papers, 27 studies were included initially in the review, of which 24 were included in the final analysis. These 24 studies had a broad range of quality and risk of bias and represented 1135 cases of CC anomalies, of which 49% were complete agenesis and the remainder were described using the term partial agenesis or nine other terms, of which five had more than one definition. Conclusions In comparison to the postnatal literature, in the prenatal literature there is much greater heterogeneity in the nomenclature and definition of CC anomalies other than complete agenesis. This heterogeneity and lack of standard definitions in the prenatal literature make it difficult to develop large multicenter pooled cohorts of patients who can be followed in order to develop a better understanding of the genetic associations and neurodevelopmental and psychological outcomes of patients with CC anomalies. As this information is important to improve counseling of these patients, a good first step towards this goal would be to develop a simpler categorization of prenatal CC anomalies that matches better the postnatal literature. © 2020 International Society of Ultrasound in Obstetrics and Gynecology

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Section: Resultsmentioning

confidence: 99%

Section: Imaging Modalitiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Heterogeneity in defining fetal corpus callosal pathology: systematic review

Mahallati

Sotiriadis

Celestin

et al. 2021

Ultrasound in Obstet & Gyne

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“…However, as discussed, an anomaly of the CSP was another neuroanatomical feature that reported within, and at times out of the isolated diagnosis of ACC. The authors of three studies specifically examined the CSP within fetuses with partial ACC, and concluded that the atypical presentation of the CSP might be considered an indirect sign of partial ACC (Karl et al, 2017;Shen et al, 2015;Zhao, Wang, & Cai, 2019). Griffiths et al, (2009) reflected on their experience and embryology and concluded that displacement or abnormality of the septum pellucidum was typical of ACC, as opposed to an absence, again suggestive of differences in interpretation.…”

Section: Neuroanatomy Additional Anomalies and Causes Of Accmentioning

confidence: 99%

Scoping Review of the Prenatal Diagnosis of Agenesis of the Corpus Callosum

Shakes¹,

Cashin²,

Hurley³

2020

Journal of Obstetric, Gynecologic & Neonatal Nursing

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“…Prenatal care and examination are crucial for gravidas to ensure healthy newborns. Congenital abnormalities of the central nervous system (CNS) are a major concern in prenatal detection of fetal brain ( 1 ), which can be screened by ultrasound (US) as a safe, cost-effective, and real-time imaging modality. Evaluation of the corpus callosum (CC) and cerebellar vermis (CV) are critical aspects of fetal brain examination.…”

Section: Introductionmentioning

confidence: 99%

A method framework of automatic localization and quantitative segmentation for the cavum septum pellucidum complex and the cerebellar vermis in fetal brain ultrasound images

Wang,

Pei,

Ouyang

et al. 2023

Quant Imaging Med Surg

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Background Early detection of central nervous system (CNS) anomalies in human embryos through prenatal screening is crucial for timely intervention and improved patient outcomes. Fetal brain mid-sagittal ultrasound images (FBMUIs) play a pivotal role as a diagnostic tool for detecting structural abnormalities. However, the automatic localization and quantitative segmentation of complex anatomical structures such as the corpus callosum-cavum septum pellucidum complex (CCC) and cerebellar vermis (CV) in FBMUIs present significant challenges. Methods To address this issue, we propose an integrated framework that combines anatomical knowledge with computer vision techniques. Our framework comprises four steps: (I) generation of average templates for CCC and CV local images using a variational autoencoder (VAE); (II) localizing the CCC by using the “Initial Localization-Accurate Localization-Result Detection” strategy, followed by segmenting it based on morphological characteristics using the “Initial Contour Fitting-Contour Iteration” strategy; (III) applying a similar strategy as CCC localization and CV segmentation; and (IV) leveraging spatial and morphological characteristics to achieve accurate localization and segmentation. Results Our CCC and CV localization and segmentation methods were validated by using 140 FBMUIs from various perspectives. The accuracy and effectiveness of our approach were demonstrated through data statistics and comparative analysis. Currently, clinical trials are being conducted on our method at Shengjing Hospital of China Medical University. Conclusions Our proposed integrated framework presents a novel solution for the automatic localization and quantitative segmentation of the CCC and CV in FBMUIs. It shows promise for early diagnosis of CNS anomalies in human embryos, offering significant clinical implications.

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Utility of indirect sonographic signs (including cavum septum pellucidum ratio) in midgestational screening for partial agenesis of corpus callosum

Cited by 5 publications

References 22 publications

Heterogeneity in defining fetal corpus callosal pathology: systematic review

Heterogeneity in defining fetal corpus callosal pathology: systematic review

Scoping Review of the Prenatal Diagnosis of Agenesis of the Corpus Callosum

A method framework of automatic localization and quantitative segmentation for the cavum septum pellucidum complex and the cerebellar vermis in fetal brain ultrasound images

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