“…Several methods such as HPLC, electrochemistry [9,10], and spectrophotometry [11,12] are used to determine LD, despite the diversity of techniques used in the determination, but there are many obstacles (Table 1), for example, the chromatography and techniques connected with it are of high cost in terms of materials and tools used, need to experience in the operation system, sample preparation, and specific conditions in separation, and on the other hand, electrochemical methods are quick to accomplish the analysis, but it displays some errors in the analysis unless it provides a special environment such as the need to clean or polish the electrodes. erefore, spectroscopic methods were used for ease, speed, accuracy, and low cost [13][14][15][16][17][18].…”