Utility of the hypertriglyceridemic waist phenotype in the cardiometabolic risk assessment of youth stratified by body mass index

Abstract

Abbreviations: BMI-Body Mass Index, WC-waist circumference; CRF-cardiorespiratory fitness; HTWP-hypertriglyceridemic waist phenotype; HDL-c-high density lipoprotein cholesterol; TC-total cholesterol; CRP-C-reactive protein; TG-triglycerides; HOMA-IR-the homeostatic model assessment of insulin resistance; SES-socioeconomic status. What is already known about this subject  Despite the clear relationship between BMI and the comorbidities associated with excess body fatness, the use of BMI is not without its limitations since by its very definition, BMI cannot distinguish between fat and fat-free mass  The presence of fasting hypertriglyceridemia alongside abdominal obesity may provide a useful indicator of visceral adiposity  The hypertriglyceridemic waist phenotype is a simple and inexpensive screening tool to identify adults at increased risk of cardiovascular disease and diabetes. What this study adds  The HTWP may confer an improved discriminatory power when compared to WC and BMI for identifying individuals with elevated cardiometabolic risk profiles.  The measurement of the hypertriglyceridemic waist phenotype appears to distinguish high risk viscerally obese individuals of the same weight status who may be more susceptible to related metabolic complications.  The addition of fasting triglycerides to waist circumference in order to identify the hypertriglyceridemic waist phenotype is a convenient and cost-effective means to identify those at greatest cardiometabolic risk, regardless of weight status. 3 Abstract: Background: It is unclear whether the Hypertriglyceridemic Waist Phenotype can be used to identify those at

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