Utility of Transbronchial Needle Aspiration in the Diagnosis of Endobronchial Lesions

Dasgupta, Asok; Jain, Prasoon; Minai, Omar A.; Sandur, Sunder; Meli, Yvonne; Arroliga, Alejandro C.; Mehta, Atul C.

doi:10.1378/chest.115.5.1237

Cited by 98 publications

(95 citation statements)

References 10 publications

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“…In the setting of non-surgical staging of lung cancer, TBNA has been shown to decrease the need for diagnostic thoracic surgery [2,3,4]. TBNA is superior to all other sampling modalities in peribronchial and submucosal disease and is on par with bronchoscopic forceps biopsy in endobronchial tumours with an average diagnostic yield of 80% [4, 5]. TBNA improves the yield of FB when added to bronchial washing, brushing and forceps biopsy [5,6,7,8,9,10].…”

Section: Introductionmentioning

confidence: 99%

“…TBNA is superior to all other sampling modalities in peribronchial and submucosal disease and is on par with bronchoscopic forceps biopsy in endobronchial tumours with an average diagnostic yield of 80% [4, 5]. TBNA improves the yield of FB when added to bronchial washing, brushing and forceps biopsy [5,6,7,8,9,10]. Despite all these positive aspects, however, TBNA is still underutilized [1].…”

Section: Introductionmentioning

confidence: 99%

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Utility of Rapid On-Site Evaluation of Transbronchial Needle Aspirates

Diacon¹,

Schuurmans²,

Theron³

et al. 2005

Respiration

147

111

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Background: Rapid on-site evaluation has been proposed as a method to improve the yield of transbronchial needle aspiration. Objectives: This study investigated whether on-site analysis facilitates routine diagnostic bronchoscopy in terms of sampling, yield and cost. Methods: Patients with lesions accessible for transbronchial needle aspiration on computed tomography were investigated. A cytopathologist screened the needle aspirates on site for the presence of diagnostic material. The bronchoscopic sampling process was adjusted according to the results. In 90 consecutive patients with neoplastic disease (n = 70; 78%), non-neoplastic disease (n = 16; 18%) or undiagnosed lesions (n = 4; 4%) we aspirated 162 lung lesions (paratracheal tumours or lymph nodes: 7%; tracheobronchial lymph nodes: 68%; other: 25%). Results: The diagnostic yield of needle aspiration was 77 and 25% in patients with neoplastic and non-neoplastic lesions, respectively. Sampling could be terminated in 64% of patients after needle aspiration had been performed as the only diagnostic modality, and on-site analysis identified diagnostic material from the first site aspirated in 50% of patients. Only in 2 patients (2%) diagnostic aspirates were not recognized on site. On-site analysis was cost effective due to savings for disposable diagnostic tools, which exceeded the extra expense for the on-site cytology service provided. Conclusions: Rapid on-site analysis of transbronchial aspirates is a highly useful, accurate and cost-effective addition to routine diagnostic bronchoscopy.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Utility of Rapid On-Site Evaluation of Transbronchial Needle Aspirates

Diacon¹,

Schuurmans²,

Theron³

et al. 2005

Respiration

147

111

View full text Add to dashboard Cite

show abstract

“…TBNA is useful in the diagnosis of endobronchial lesion because it causes less bleeding than brushing or biopsy. As per Dasgupta et al [8], TBNA provides diagnosis in 95.6% of patients with endobronchial lesions, surpassing the combined yield of washing, brushing and biopsy. Subsequently various workers have reported the usefulness of TBNA, even in the absence of an endobronchial disease [7].…”

Section: Discussionmentioning

confidence: 86%

Flexible Bronchoscopy in the Evaluation of Mediastinal and Hilar Lymphadenopathy

Rai

Bhattacharyya

Choudhary³

2007

Medical Journal Armed Forces India

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“…Kvale et al [19] found no additional advantage of BW over a combination of BB and EBB. Dasgupta et al [20] found BW to be least useful of the three bronchoscopic diagnostic techniques.…”

Section: Discussionmentioning

confidence: 97%