The amount of household waste such as fruit peel waste which is organic waste will have an impact on the environment. The organic waste can be processed into eco-enzyme. Eco-enzyme is obtained from the fermentation process. The fruit peel used are watermelon, pineapple, banana, and orange. The fermentation process used fruit peel waste, water, and sugar in a ratio of 3 : 10 : 1. After 90 days of the fermentation process, filtering is carried out to obtain the filtrate which is an eco-enzyme. The obtained of eco-enzyme has brown and a sour aroma. Eco-enzyme positive has contains acetic acid and lactic acid, also flavonoids, alkaloids, and saponins. This eco-enzyme can be used to cleaned the floors, as a fertilizer, and others. It has changed what was a waste at the first, into something that has many benefits, by processed the waste in the right way.