Utilization of therapeutic intervention to prevent mother to child transmission of HIV in a teaching hospital in Kolkata, India

Chaudhuri, Snehamay; Mundle, Malay; Konar, Hiralal; Das, Chandana; Talukdar, Arunansu; Ghosh, Uday Sankar

doi:10.1111/j.1447-0756.2009.01161.x

Cited by 12 publications

(19 citation statements)

References 15 publications

(22 reference statements)

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“…In this present study, the overall acceptance of HIV testing after counseling with 'opt-out' approach was 98.97% (11,390/11,508). Similar acceptance rate of 100% and 96% was reported by Parameswari et al and Chaudhari et al in India respectively 8,9 . Study conducted by Joshi et.al.…”

Section: Discussionsupporting

confidence: 74%

“…Similar seroprevalence of 0.56%, 0.41%, and 0.40% was reported by Mandal et al, Giri et 8,15 . Also the lower prevalence of 0.17% was reported by Chaudhari et al 9 . This wide variability in HIV seroprevalence among antenatal women may be attributed to the difference in health seeking and risk behaviors in different parts within and outside India which mostly depends on socio cultural milieu of the community.…”

Section: Sd-standard Deviation Ci-confidence Intervalsmentioning

confidence: 73%

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Utilization of the prevention of parent-to-child transmission of HIV (PPTCT) services in a tertiary care hospital, Odisha, India

Dash

Misra

Subudhi

2014

Bangladesh J Med Sci

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Aims: To assess seroprevalence of HIV among antenatal women and the extent of utilization of interventions to minimize the risk of mother-to-child transmission. Study Design: Descriptive cross-sectional study was carried out among antenatal women who attended integrated counseling and testing center (ICTC) of HIV. Sample sizes were determined from the number of pregnant women that attended ICTC. Place and Duration of Study: Data and samples were collected from a tertiary care hospital, Odisha, India during January 2009 to December 2012. Methodology: All pregnant women were counseled and tested for HIV by rapid test. All HIV-seropositive antenatal women (ANW) were linked to services and followed up for institutional delivery, single-dose nevirapine (sdNVP) prophylaxis, infant feeding options and testing of children at 18 months. Results: Out of 11,508 ANW registered and pretest counseled, 11,390 (98.97%) accepted HIV testing. Sixty women were found to be seropositive, thus showed seroprevalence rate of 0.53% (60/11,390). CD4 testing was carried out in all ANW and five (8.33%) were eligible for antiretroviral therapy (ART). Seven (11.67%) had opted for medical termination of pregnancy (MTP). All 48 ANW delivered institutionally, only 7 (14.58%) received cesarean delivery. Out of 46 live births, 5 (10.87%) ANW were on ART, 35/41 (85.37%) received sdNVP mother baby-pair prophylaxis and only 8/46 (17.39%) mother opted for replacement feeding. Twenty one children have reached 18 months till date and among them three (14.29%) were HIV-seropositive. All three were delivered vaginally, received sdNVP prophylaxis and were exclusively breast fed for 6 months. Conclusion: The HIV-seroprevalence rate among antenatal women was 0.53% and mother-to-child transmission (MTCT) rate was 14.29%. Reduction in MTCT rate needs pre or early antenatal HIV testing, prenatal antiretroviral medication, preference for cesarean delivery, 100% antiretroviral prophylaxis coverage and education on avoidance of breast-feeding. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18300 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.163-169

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Section: Discussionsupporting

confidence: 74%

Section: Sd-standard Deviation Ci-confidence Intervalsmentioning

confidence: 73%

Utilization of the prevention of parent-to-child transmission of HIV (PPTCT) services in a tertiary care hospital, Odisha, India

Dash

Misra

Subudhi

2014

Bangladesh J Med Sci

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“…10 The WHO and UNAID introduced a routine opt-out approach in countries with high prevalence. 11 In the present study, the overall acceptance of the HIV testing with opt-out approach was 83.85% (15, 14,15 This emphasizes there is need for good counseling skills by the counselor to achieve both counselling and HIV testing close to 100%. We observed that, majority of seropositive pregnant women were married, primigravidae, residence of rural areas with low socioeconomic status, were either illiterate or studied up to primary level and not used any contraceptives.…”

Section: Discussionmentioning

confidence: 93%

Declining Hiv Seroprevalence Among Pregnant Women in South Odisha, India: A Six and Half Year Tertiary Care Hospital Based Study

Dash

Mohanty

Sahu

et al. 2012

Int J of Biomed & Adv Res

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Background: Acquired Immune Deficiency Syndrome (AIDS) caused by Human Immunodeficiency Virus (HIV) has emerged as the greatest threat to human existence. Estimating the rate and trends of HIV seroprevalence among pregnant women provides essential information for an effective implementation of Prevention of Parent to Child Transmission of HIV (PPTCT) programme and for monitoring its spread within different parts of the country. Objective: As few studies are available from India on HIV prevalence among the antenatal population, a study at a tertiary care hospital in southern Odisha was carried out to know the current trends of seroprevalence in this group. Methods: Blood samples were collected from pregnant women attending antenatal clinic and Integrated Counselling and Testing Centre II (ICTC II) after pre test counselling and informed consent from November 2005 to April 2012. The samples were tested for HIV antibodies as per WHO and NACO guidelines. Result: Among 18,905 pregnant women counseled, 15,853 (83.85%) were accepted for HIV testing. From the total 15,853 tested in six and half years, 0.66% women were found to be HIV seropositive. The mean age of HIV positive women was 24.31 years (SD ± 3.9 yrs). The HIV seroprevalence rates showed a declining trend from 1.53% in 2006 to 0.34% in 2012. Among seropositive women majority (43.8%) were in the age group of 25-29 years. Conclusion: Declining seroprevalence rate indicate prevention campaigns are working, condom usage and preventive sexual behavior has increased.

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“…As on 31 st August 2016 in India there are 20,756 Integrated Counselling and Testing Centres (ICTC), most of these in government hospitals, which offer PPTCT services to pregnant women. 9 Globally over the past few years the PPTCT interventions have transitioned from the use of single dose Nevirapine to the use of multidrug antiretroviral therapy, to efficiently bring down the rate of transmission of HIV from mother-to-child to the level of less than 5%.7 Screening of HIV in pregnant women plays the most important role in reducing mother to child 15,16 To achieve high rates of counselling and testing, good counselling skills and experience of the counsellor is fundamental.…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of HIV in ANC clinic attendees and utilization of PPTCT services at a tertiary care hospital of western Rajasthan, India

Mehta¹,

Bhati²,

Mehta³

2017

Int J Reprod Contracept Obstet Gynecol

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Background: Human immunodeficiency virus (HIV) infection in pregnant women has an important role in its spread to paediatric population by means of vertical transmission. Effective utilization of PPTCT services can reduce this spread. This study aims to determine seroprevalence of HIV in antenatal women, demographic factors of seropositive women and utilization of PPTCT services to minimize the risk of mother to child transmission.Methods: A retrospective study was done among pregnant women attending antenatal clinic of a tertiary care hospital within a period of two years from November 2013 to October 2015. Pre-test counselling, HIV testing, and post-test counselling were done as per NACO guidelines. Antiretroviral prophylaxis was given to seropositive women and their children. Analysis of demographic data of seropositive women and assessment of utilization of PPTCT services was done.Results: Out of 40,913 new antenatal registrations 26,803 (65.58%) women attended pre test counselling and 24716(60.41%) of them accepted HIV testing. Thirty-eight women were found to be seropositive with a seroprevalence rate of 0.16%. Majority of seropositve women were young primigravida, illiterate housewives belonging to rural area. Eight out of 33 partners of seropositive women tested, were found to be seronegative. Out of the 38 seropositive women, 4(10.52%) opted for pregnancy termination, and 31(81.57%) had delivery in our institution. All mother and baby pairs received antiretroviral prophylaxis.Conclusions: Seroprevalence of HIV infection in antenatal women is relatively low in this region than the national average and acceptance of therapeutic interventions to reduce the mother to child transmission is high. There is scope to improve acceptance of counselling and testing of HIV.

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Utilization of therapeutic intervention to prevent mother to child transmission of HIV in a teaching hospital in Kolkata, India

Abstract: As uptake of testing is high and detection of HIV-infected women in pregnancy remains very low, a radical rethinking of policies on therapeutic intervention and their implementation now needs to be undertaken.

Cited by 12 publications

References 15 publications

Utilization of the prevention of parent-to-child transmission of HIV (PPTCT) services in a tertiary care hospital, Odisha, India

Utilization of the prevention of parent-to-child transmission of HIV (PPTCT) services in a tertiary care hospital, Odisha, India

Declining Hiv Seroprevalence Among Pregnant Women in South Odisha, India: A Six and Half Year Tertiary Care Hospital Based Study

Seroprevalence of HIV in ANC clinic attendees and utilization of PPTCT services at a tertiary care hospital of western Rajasthan, India

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