We present synthetic observations for the first generations of galaxies in the Universe and make predictions for future deep field observations for redshifts greater than 6. Due to the strong impact of nebular emission lines and the relatively compact scale of H ii regions, high resolution cosmological simulations and a robust suite of analysis tools are required to properly simulate spectra. We created a software pipeline consisting of FSPS, Hyperion, Cloudy and our own tools to generate synthetic IR observations from a fully three-dimensional arrangement of gas, dust, and stars. Our prescription allows us to include emission lines for a complete chemical network and tackle the effect of dust extinction and scattering in the various lines of sight. We provide spectra, 2-D binned photon imagery for both HST and JWST IR filters, luminosity relationships, and emission line strengths for a large sample of high redshift galaxies in the Renaissance Simulations. Our resulting synthetic spectra show high variability between galactic halos with a strong dependence on stellar mass, metallicity, gas mass fraction, and formation history. haloes with the lowest stellar mass have the greatest variability in [O iii]/Hβ, [O iii] and C iii] while haloes with higher masses are seen to show consistency in their spectra and [O iii] equivalent widths (EW) between 1Å and 10Å. Viewing angle accounted for three-fold difference in flux due to the presence of ionized gas channels in a halo. Furthermore, JWST colour plots show a discernible relationship between redshift, colour, and mean stellar age.